Anastasi G, Bruschetta D, De Leo S, Magaudda L, Santoro G, Trimarchi F
Dipartimento di Biomorfologia, Università di Messina.
Minerva Stomatol. 1990 Sep;39(9):705-14.
Aim of our present work is to investigate with the SEM the process of enamel mineralization in the lower incisors of albino rats submitted for 21 days (a single amelogenetic cycle) to an hyperfluoric diet (five folds more than the normal). Our observations were performed on specimens fractured 8, 12 and 16 mm from the cervical loop transversally along the major axis of the incisor. It was demonstrated that the three different phases of enamel maturation were slower, so that, when the incisor erupted, mineralization was not completed and localized areas of demineralization were present. The authors are of the opinion that all morphological changes are dependent on the effect of fluoride on ameloblasts, either during their secretory or modulatory phases. On the basis of our results attention is pointed on the possible lesions of the enamel dependent from an unwary fluoride administration, particularly when decidual teeth are still present.
我们当前工作的目的是利用扫描电子显微镜研究白化大鼠下切牙的釉质矿化过程。这些大鼠食用高氟饮食（是正常饮食的五倍）21天（一个单一的成釉细胞周期）。我们的观察是在沿着切牙长轴从颈环横向8、12和16毫米处折断的标本上进行的。结果表明，釉质成熟的三个不同阶段都变慢了，因此，当切牙萌出时，矿化尚未完成，并且存在局部脱矿区域。作者认为，所有形态学变化都取决于氟在成釉细胞分泌期或调节期对其产生的影响。基于我们的研究结果，需关注因不慎摄入氟而可能导致的釉质损害，尤其是在乳牙仍存在的时候。
