Liu Xin, Bai Xiao-feng, Huang Shao-hui
Department of Head and Neck Cancer Surgery, School of Stomatology, China Medical University, Shenyang 110002, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2012 Jun;47(6):350-3. doi: 10.3760/cma.j.issn.1002-0098.2012.06.007.
To evaluate the value of sentinel lymph node biopsy in diagnosis of cervical metastasis in patients with early oral squamous cell carcinoma.
Cochrane library, evidence-based medicine (EBM), PubMed, China national knowledge internet (CNKI) were searched for 2001 - 2011 literatures on sentinel lymph node biopsy in patients with oral squamous cell carcinoma as early diagnosis of cervical metastasis. The results were analysed by using Meta-analysis software Metadisc1.4.
There were 12 studies in which, a total of 793 patients with oral squamous cell carcinoma were involved in Meta-analysis. The combined sensitivity and specificity were 0.86 (95%CI: 0.81 - 0.90) and 0.99 (95%CI: 0.98 - 1.00) respectively.
For early oral cancer patients, the sensitivity and specificity of sentinel lymph node biopsy are relatively high. The sentinel lymph node biopsy could be used to select which patients need neck dissection.
评估前哨淋巴结活检在早期口腔鳞状细胞癌患者颈部转移诊断中的价值。
检索考克兰图书馆、循证医学（EBM）、PubMed、中国知网（CNKI）中2001年至2011年有关前哨淋巴结活检用于口腔鳞状细胞癌患者颈部转移早期诊断的文献。采用Meta分析软件Metadisc1.4对结果进行分析。
共有12项研究纳入Meta分析，涉及793例口腔鳞状细胞癌患者。合并敏感度和特异度分别为0.86（95%CI：0.81 - 0.90）和0.99（95%CI：0.98 - 1.00）。
对于早期口腔癌患者，前哨淋巴结活检的敏感度和特异度相对较高。前哨淋巴结活检可用于选择哪些患者需要行颈部清扫术。
