Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science & Technology, Shanghai 200237, PR China.
Chem Commun (Camb). 2012 Oct 11;48(79):9897-9. doi: 10.1039/c2cc35080g. Epub 2012 Aug 30.
Based on 6-hydroxyindole BODIPY with a Schiff-base structure, NIR fluorescence with impressively high selectivity is triggered by deprotonation of the phenol group upon binding with Zn(2+) due to the chelation-enhanced fluorescence effect, thus realizing a promising application in bioimaging of Zn(2+).
基于具有席夫碱结构的 6-羟基吲哚 BODIPY,酚羟基的去质子化会引发近红外荧光显著增强的选择性,这是由于螯合增强荧光效应,从而实现了在 Zn(2+)生物成像中的有前景的应用。