SB Izmir Tepecik Teaching Research Hospital, Pathology Department, Turkey.
Radiol Oncol. 2011 Mar;45(1):53-8. doi: 10.2478/v10019-010-0039-3. Epub 2010 Sep 22.
Metastases to the thyroid are encountered rarely in clinical practice, but the number of cases seems to have increased in recent years. The reason of this increase may be a more frequent use of fine-needle aspiration biopsy (FNAB) and the use of more sophisticated, complicated imaging techniques in patients with thyroid masses. Also, in addition to these reasons, the use of more organo-specific immunohistochemical antibodies in the examination of surgical specimens may affect the differential diagnosis of malignant tumours.
Three metastatic tumours to thyroid were found in the retrospective review of malignant thyroid tumours diagnosed between January 1993 and December 2007. The primary tumours were clear cell carcinoma of the kidney, squamous cell carcinoma of the lung and breast carcinoma-ductal type.
A detailed clinical history, careful histological examination and essential immunohistochemistry helped in attaining the correct diagnosis.
在临床实践中,甲状腺转移瘤很少见,但近年来病例似乎有所增加。这种增加的原因可能是细针抽吸活检(FNAB)的使用更加频繁,以及甲状腺肿块患者使用了更复杂、更先进的成像技术。此外,除了这些原因之外,在检查手术标本时使用更多器官特异性免疫组织化学抗体也可能影响恶性肿瘤的鉴别诊断。
在回顾性分析 1993 年 1 月至 2007 年 12 月间诊断的恶性甲状腺肿瘤时,发现了 3 例甲状腺转移瘤。原发肿瘤分别为肾透明细胞癌、肺鳞状细胞癌和乳腺导管癌。
详细的临床病史、仔细的组织学检查和必要的免疫组织化学有助于做出正确的诊断。