Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Radiol Oncol. 2011 Sep;45(3):184-8. doi: 10.2478/v10019-011-0010-y. Epub 2011 Mar 29.
We evaluated the feasibility of outlining the body with scattered photons using a low dose intradermal injection of the radiotracer. PATIENTS AND METHODS.: Sixty breast cancer patients were included into the study. 30 minutes post radiotracer injection static lymphoscintigraphy images were acquired using low energy high resolution collimator in anterior and lateral views. For patients with 2-day protocol another set of images was taken 20 hours post-injection. Two photopeaks were used during imaging: 1-Tc-99m (130-150 keV) and 2- Scatter photons (60-120). The fusion image of these two images was constructed by NM-NM fusion workflow of the workstation. The usual body outline of the patients was also acquired in 20 cases using the external flood source without moving the patients from their positions.
The early (30 minute image) scatterograms of the patients clearly showed the contour of the body. The 20 hour scatterograms were not as high quality as the corresponding early images. The constructed overlaid images showed the location of the axillary sentinel nodes and the body contours clearly for early scatterograms but not the delayed (20 hour) ones. The processing of the images for the reconstruction of overlaid scatterograms took the mean time of 10±5 seconds.
Imaging the scattered photons is feasible for the intradermal low dose injection of the radiotracers in order to outline the body contour. This imaging method does not increase the radiation exposure of the patients or operators and does not extend the time of imaging either.
我们评估了使用放射性示踪剂皮内低剂量注射勾勒身体轮廓的可行性。
将 60 例乳腺癌患者纳入本研究。在放射性示踪剂注射后 30 分钟,使用低能高分辨率准直器在前后位采集静态淋巴闪烁显像图像。对于 2 天方案的患者,在注射后 20 小时再采集另一组图像。在成像过程中使用了两个光峰:1-Tc-99m(130-150keV)和 2-散射光子(60-120keV)。通过工作站的 NM-NM 融合工作流程构建这两种图像的融合图像。在 20 例患者中,还使用外部洪水源在不移位患者的情况下获得了患者的常规身体轮廓。
患者的早期(30 分钟图像)散射图清楚地显示了身体轮廓。20 小时的散射图不如相应的早期图像质量高。构建的叠加图像清楚地显示了腋窝前哨淋巴结和身体轮廓的位置,但对于延迟(20 小时)图像则不然。重建叠加散射图的图像处理平均需要 10±5 秒。
为了勾勒身体轮廓,可以对放射性示踪剂的皮内低剂量注射进行散射光子成像。这种成像方法不会增加患者或操作人员的辐射暴露,也不会延长成像时间。