Krynyckyi Borys R, Shafir Michail K, Kim Suk Chul, Kim Dong Wook, Travis Arlene, Moadel Renee M, Kim Chun K
Division of Nuclear Medicine, Department of Radiology, The Mount Sinai School of Medicine and Hospital, New York, New York, USA.
Int Semin Surg Oncol. 2005 Nov 8;2:25. doi: 10.1186/1477-7800-2-25.
Current trends in patient care include the desire for minimizing invasiveness of procedures and interventions. This aim is reflected in the increasing utilization of sentinel lymph node biopsy, which results in a lower level of morbidity in breast cancer staging, in comparison to extensive conventional axillary dissection. Optimized lymphoscintigraphy with triangulated body marking is a clinical option that can further reduce morbidity, more than when a hand held gamma probe alone is utilized. Unfortunately it is often either overlooked or not fully understood, and thus not utilized. This results in the unnecessary loss of an opportunity to further reduce morbidity. Optimized lymphoscintigraphy and triangulated body marking provides a detailed 3 dimensional map of the number and location of the sentinel nodes, available before the first incision is made. The number, location, relevance based on time/sequence of appearance of the nodes, all can influence 1) where the incision is made, 2) how extensive the dissection is, and 3) how many nodes are removed. In addition, complex patterns can arise from injections. These include prominent lymphatic channels, pseudo-sentinel nodes, echelon and reverse echelon nodes and even contamination, which are much more difficult to access with the probe only. With the detailed information provided by optimized lymphoscintigraphy and triangulated body marking, the surgeon can approach the axilla in a more enlightened fashion, in contrast to when the less informed probe only method is used. This allows for better planning, resulting in the best cosmetic effect and less trauma to the tissues, further reducing morbidity while maintaining adequate sampling of the sentinel node(s).
当前患者护理的趋势包括尽量减少手术和干预的侵入性。这一目标体现在前哨淋巴结活检的使用日益增加,与广泛的传统腋窝清扫相比,前哨淋巴结活检在乳腺癌分期中导致的发病率较低。采用三角体表标记的优化淋巴闪烁造影是一种临床选择,与仅使用手持γ探针相比,它可以进一步降低发病率。不幸的是,它常常被忽视或未被充分理解,因此未得到应用。这导致不必要地失去了进一步降低发病率的机会。优化淋巴闪烁造影和三角体表标记可在首次切开前提供前哨淋巴结数量和位置的详细三维图谱。淋巴结的数量、位置、基于出现时间/顺序的相关性,所有这些都可以影响:1)切口位置;2)清扫范围;3)切除的淋巴结数量。此外,注射可能会出现复杂的模式。这些包括明显的淋巴管、假前哨淋巴结、梯队和反梯队淋巴结,甚至污染,仅用探针更难处理这些情况。与仅使用信息较少的探针方法相比,通过优化淋巴闪烁造影和三角体表标记提供的详细信息,外科医生可以更明智地处理腋窝。这有助于更好地规划,从而获得最佳的美容效果,减少对组织的创伤,在保持对前哨淋巴结进行充分取样的同时进一步降低发病率。