Yamamoto Takahiro, Yano Shigetoshi, Kuroda Jun-Ichiro, Hasegawa Yu, Hide Takuichiro, Kuratsu Jun-Ichi
Department of Neurosurgery, Faculty of Life Sciences, Kumamoto University School of Medicine, 1-1-1, Honjo, Kumamoto 861-8556, Japan.
Case Rep Endocrinol. 2012;2012:826901. doi: 10.1155/2012/826901. Epub 2012 Aug 15.
Pituitary apoplexy is a rare clinical syndrome attributable to hemorrhage or hemorrhagic infarction of pituitary tumors or pituitary glands. The features of pituitary apoplexy associated with the endocrine stimulation test remain to be elucidated and the importance of surgical treatment has not been discussed enough. We report two rare patients who were treated successfully by endoscopic endonasal transsphenoidal surgery within several hours after onset of pituitary apoplexy associated with the endocrine stimulation test. Their postoperative course was uneventful. We reviewed earlier reports on this clinical entity, document its features especially as related to the endocrine stimulation test, discuss the significance of immediate surgical treatment, and present our treatment outcomes. Performing only conservative treatment is not recommended. We suggest that the necessity of endocrine stimulation test should be assessed on a case-by-case basis and in patients subjected to the test, and neurosurgical support should be sought.
垂体卒中是一种罕见的临床综合征，归因于垂体肿瘤或垂体的出血或出血性梗死。与内分泌刺激试验相关的垂体卒中的特征仍有待阐明，并且手术治疗的重要性尚未得到充分讨论。我们报告了两名罕见患者，他们在与内分泌刺激试验相关的垂体卒中发作后数小时内通过鼻内镜经蝶窦手术成功治疗。他们的术后过程平稳。我们回顾了关于这一临床实体的早期报告，记录其特征，特别是与内分泌刺激试验相关的特征，讨论立即手术治疗的意义，并展示我们的治疗结果。不建议仅进行保守治疗。我们建议应根据具体情况评估内分泌刺激试验的必要性，对于接受该试验的患者，应寻求神经外科支持。
