Uttley W S, Atkinson B, Adams A, Shirling D
J Inherit Metab Dis. 1978;1(2):75-7. doi: 10.1007/BF01801849.
Urinary excretion of cyclic adenosine monophosphate (cAMP) is assessed in response to pitressin stimulation in three patients with nephrogenic diabetes insipidus, four carriers and seven controls. There is no significant difference in cAMP excretion between these groups when corrected for surface area, nor is there any significant increase in excretion after pitressin stimulation. There is very close correlation between urinary cAMP and both urinary concentration and urinary creatinine excretion. Urinary cAMP after pitressin stimulation does not discriminate between carriers of nephrogenic diabetes insipidus and control subjects.
对三名肾性尿崩症患者、四名携带者和七名对照者，评估了抗利尿激素刺激后环磷酸腺苷（cAMP）的尿排泄情况。校正体表面积后，这些组之间的cAMP排泄无显著差异，抗利尿激素刺激后排泄也无显著增加。尿cAMP与尿浓缩及尿肌酐排泄之间存在非常密切的相关性。抗利尿激素刺激后的尿cAMP无法区分肾性尿崩症携带者和对照者。
