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声刺激对使用刺激频率和失真产物耳声发射测量的耳蜗调谐的影响。

Effect of contralateral acoustic stimulation on cochlear tuning measured using stimulus frequency and distortion product OAEs.

机构信息

Institute of Sound and Vibration Research, University of Southampton, Highfield, Southampton, UK.

出版信息

Int J Audiol. 2012 Dec;51(12):892-9. doi: 10.3109/14992027.2012.709641. Epub 2012 Aug 30.

Abstract

OBJECTIVE

To study whether a change in cochlear tuning, measured using OAEs, could be detected due to contralateral activation of the efferent system using broadband noise.

DESIGN

Cochlear tuning measures based on SFOAE phase gradients and SFOAE-2TS 'Q' were used to test this hypothesis. SFOAE magnitude and phase gradient were measured using a pure-tone sweep from 1248 to 2496 Hz at 50 dB SPL. 2TS curves of SFOAE were recorded with a suppressor frequency swept from 1120 to 2080 Hz at 50 dB SPL. DPOAE f2-sweep phase gradient was also obtained to allow comparisons with the literature. All three assays were performed across with- and no-CAS conditions.

STUDY SAMPLE

Twenty-two young, normal-hearing adults.

RESULTS

CAS did not produce a statistically significant change in the tuning metric in any of the OAE methods used, despite producing significant reductions in the OAE magnitude.

CONCLUSION

It is unknown whether this insensitivity to CAS is due to an insensitivity of these three measures to cochlear mechanical tuning. The results suggest that any changes in tuning induced by CAS that may occur are small and difficult to detect using the OAE measurement paradigms used here.

摘要

目的

研究使用宽带噪声是否可以通过对传出系统的对侧激活来检测到耳声发射(OAE)测量中的耳蜗调谐变化。

设计

使用 SFOAE 相位梯度和 SFOAE-2TS“Q”的耳蜗调谐测量来检验这一假设。使用纯音扫频从 1248 到 2496 Hz(50 dB SPL)测量 SFOAE 的幅度和相位梯度。使用抑制频率从 1120 到 2080 Hz(50 dB SPL)扫频记录 SFOAE 的 2TS 曲线。还获得了 DPOAE f2-sweep 相位梯度,以便与文献进行比较。所有三种测定方法均在有和无对侧激活条件下进行。

研究样本

22 名年轻、听力正常的成年人。

结果

尽管对 OAE 幅度产生了显著的降低,但对侧激活并没有在任何使用的 OAE 方法中产生统计学上显著的调谐度量变化。

结论

目前尚不清楚这种对侧激活的不敏感性是由于这三种测量方法对耳蜗机械调谐不敏感所致。结果表明,使用这里使用的 OAE 测量范式,对侧激活引起的任何调谐变化都很小,难以检测到。

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