Vyas Arpita Kalla, White Neil H
Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Washington University in Saint Louis and Saint Louis Children's Hospital, Saint Louis, MO 63110, USA.
Case Rep Endocrinol. 2011;2011:424712. doi: 10.1155/2011/424712. Epub 2011 Sep 11.
Vitamin A intoxication secondary to over-the-counter nutritional supplements and from its use in acne treatment has been described. However, there have been very few case reports of chronic hypervitaminosis A leading to hypercalcemia in the pediatric population. This paper describes a boy with hypercalcemia secondary to chronic vitamin A intoxication in the context of vitamin A usage for therapy of autism. In addition to discontinuation of vitamin A, hyperhydration, and furosemide, the hypercalcemia in this patient required the use of prednisone and pamidronate to normalize the calcium.
已有关于非处方营养补充剂及用于痤疮治疗导致维生素A中毒的描述。然而,在儿科人群中,因慢性维生素A过多症导致高钙血症的病例报告却非常少见。本文描述了一名男孩,在使用维生素A治疗自闭症的背景下,因慢性维生素A中毒继发高钙血症。除停用维生素A、进行补液及使用速尿外,该患者的高钙血症还需要使用泼尼松和帕米膦酸来使血钙恢复正常。