Garbers Eike, Reuther Falk, Delling Gunther
Klinik für Unfallchirurgie und Orthopaedie, DRK Kliniken Berlin Koepenick, Salvador-Allende-Straße 2-8, 12559 Berlin, Germany.
Case Rep Rheumatol. 2011;2011:565142. doi: 10.1155/2011/565142. Epub 2011 Oct 19.
Massive osteolysis known as Gorham-Stout disease is a rare idiopathic disorder typically affecting long bones in a unifocal pattern. Angiomatosis is strongly connected to the osteolysis. Weather angiomatosis is the cause or the result of osteolysis is subject of intense discussion (Kawasaki et al. (2003), Möller et al. (1999), Radhakrishnan and Rockson (2008)). There are about 200 cases described since 1955. Our patient is a 77-year-old female patient with osteolyses of both shoulders involving the proximal humerus, lateral clavicle, and the glenoid. Under bisphosphonate therapy, the progressive osteolysis stopped on the right side and showed progression on the left. With the patient complaining about severe rest pain and impaired function, we performed surgical reconstruction by implantation of total shoulder prosthesis three months after onset of symptoms. Our case shows a possibility of primary and early surgical reconstruction with good clinical outcome.
被称为戈勒姆-斯托特病的大块骨质溶解是一种罕见的特发性疾病，通常以单灶性模式影响长骨。血管瘤病与骨质溶解密切相关。血管瘤病是骨质溶解的原因还是结果，这是激烈讨论的主题（川崎等人（2003年）、默勒等人（1999年）、拉德哈克里什南和罗克森（2008年））。自1955年以来，大约有200例病例被描述。我们的患者是一名77岁的女性，双肩骨质溶解，累及肱骨近端、锁骨外侧和关节盂。在双膦酸盐治疗下，右侧进行性骨质溶解停止，左侧则进展。由于患者抱怨严重的静息痛和功能受损，我们在症状出现三个月后通过植入全肩关节假体进行了手术重建。我们的病例显示了早期进行初次手术重建并取得良好临床效果的可能性。
