• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

On the specificity of naloxone as an opiate antagonist.

作者信息

Sawynok J, Pinsky C, LaBella F S

出版信息

Life Sci. 1979 Nov 5;25(19):1621-32. doi: 10.1016/0024-3205(79)90403-x.

DOI:10.1016/0024-3205(79)90403-x
PMID:229377
Abstract
摘要

相似文献

1
On the specificity of naloxone as an opiate antagonist.关于纳洛酮作为阿片拮抗剂的特异性。
Life Sci. 1979 Nov 5;25(19):1621-32. doi: 10.1016/0024-3205(79)90403-x.
2
[Opiate receptors, endorphins and their antagonists].[阿片受体、内啡肽及其拮抗剂]
Anesteziol Reanimatol. 1984 May-Jun(3):52-61.
3
Stereospecific effects of opiate antagonists on superficial and deep nociception and on motor activity suggest involvement of endorphins on different opioid receptors.
Life Sci. 1979 May 21;24(21):1959-69. doi: 10.1016/0024-3205(79)90306-0.
4
The gamma(2)-MSH peptide mediates a central analgesic effect via a GABA-ergic mechanism that is independent from activation of melanocortin receptors.γ（2）-促黑素细胞激素肽通过一种不依赖黑素皮质素受体激活的γ-氨基丁酸能机制介导中枢镇痛作用。
Neuropeptides. 2001 Feb;35(1):50-7. doi: 10.1054/npep.2000.0843.
5
Mouse-killing in rats induces a naloxone-blockable increase in nociceptive threshold.大鼠捕杀小鼠会导致伤害性感受阈值出现可被纳洛酮阻断的升高。
Eur J Pharmacol. 1980 May 2;63(2-3):195-8. doi: 10.1016/0014-2999(80)90445-8.
6
Effects of naloxone and hypophysectomy on electroconvulsive shock-induced analgesia.纳洛酮和垂体切除术对电休克诱导镇痛的影响。
Brain Res. 1981 Mar 9;208(1):230-3. doi: 10.1016/0006-8993(81)90639-9.
7
Multiple opioid receptor systems in brain and spinal cord: Part 2.大脑和脊髓中的多种阿片受体系统：第2部分。
Eur J Anaesthesiol. 1984 Sep;1(3):201-43.
8
Antinociceptive response to nitrous oxide is mediated by supraspinal opiate and spinal alpha 2 adrenergic receptors in the rat.大鼠对一氧化二氮的抗伤害感受反应是由脊髓上阿片类受体和脊髓α2肾上腺素能受体介导的。
Anesthesiology. 1996 Oct;85(4):846-52. doi: 10.1097/00000542-199610000-00020.
9
Kappa-receptor antagonist reverse 'non-opioid' stress-induced analgesia.
Brain Res. 1984 Jun 18;304(1):153-6. doi: 10.1016/0006-8993(84)90872-2.
10
Chronic lithium administration alters the interaction between opiate antagonists and opiate receptors in vivo.
Neuropharmacology. 1981 Jun;20(6):587-91. doi: 10.1016/0028-3908(81)90212-4.

引用本文的文献

1
Structural snapshots capture nucleotide release at the μ-opioid receptor.结构快照捕捉到μ-阿片受体处的核苷酸释放。
Nature. 2025 Nov 5. doi: 10.1038/s41586-025-09677-6.
2
A Radar-Based Opioid Overdose Detection Device for Public Restrooms: Design, Development, and Evaluation Study.一种用于公共卫生间的基于雷达的阿片类药物过量检测装置：设计、开发与评估研究
JMIR Biomed Eng. 2023 Oct 24;8:e51754. doi: 10.2196/51754.
3
Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP.
使用新型长效纳洛酮纳米颗粒cNLX-NP评估芬太尼诱导的呼吸抑制的逆转率。
Front Psychiatry. 2024 Mar 14;15:1366186. doi: 10.3389/fpsyt.2024.1366186. eCollection 2024.
4
Assessment of naloxone as a therapeutic for inhaled carfentanil in the ferret.对纳洛酮作为雪貂吸入卡芬太尼治疗药物的评估。
Toxicol Rep. 2020;7:1112-1120. doi: 10.1016/j.toxrep.2020.08.019. Epub 2020 Aug 22.
5
Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7.内源性阿片类物质导致缺乏钠通道Nav1.7的人类和小鼠对疼痛不敏感。
Nat Commun. 2015 Dec 4;6:8967. doi: 10.1038/ncomms9967.
6
Effects of acute stressors on itch- and pain-related behaviors in rats.急性应激源对大鼠瘙痒和疼痛相关行为的影响。
Pain. 2012 Sep;153(9):1890-1897. doi: 10.1016/j.pain.2012.05.032. Epub 2012 Jul 5.
7
[Oral administration of slow-release naloxone for prevention of constipation but not analgesia following oral morphine.].口服缓释纳洛酮预防口服吗啡后的便秘而非镇痛作用。
Schmerz. 1993 Dec;7(4):314-21. doi: 10.1007/BF02529868.
8
Presynaptic opioid receptors on noradrenergic and serotonergic neurons in the human as compared to the rat neocortex.与大鼠新皮层相比，人类去甲肾上腺素能和5-羟色胺能神经元上的突触前阿片受体。
Br J Pharmacol. 2006 Jul;148(6):795-806. doi: 10.1038/sj.bjp.0706782. Epub 2006 Jun 5.
9
Repeated restraint stress reduces opioid receptor binding in different rat CNS structures.
Neurochem Res. 2005 Jan;30(1):1-7. doi: 10.1007/s11064-004-9679-2.
10
Laser acupuncture: past, present, and future.激光针灸：过去、现在与未来。
Lasers Med Sci. 2004;19(2):69-80. doi: 10.1007/s10103-004-0296-8.