Department of Pathology (MC 847), UIC, College of Medicine, 840 S Wood St, Room 110 CSN, Chicago, IL 60612, USA.
Arch Pathol Lab Med. 2012 Sep;136(9):1001-3. doi: 10.5858/arpa.2011-0221-CR.
A Pneumocystis jiroveci infection-associated mass clinically mimicking a malignancy (ie, pseudotumor) is rare and usually occurs in the lung in association with Pneumocystis pneumonia. Pneumocystis jiroveci pseudotumors of the small intestine are extremely rare and represent an unusual form of disseminated P jiroveci infection. We present a case of small-intestine P jiroveci pseudotumor as an acquired immunodeficiency syndrome-presenting illness in a patient with coinfection with cytomegalovirus, no pulmonary symptoms, and no known risk factors for human immunodeficiency virus infection. This case reinforces the potential importance of cytomegalovirus coinfection in the disseminated form of Pneumocystis infection and illustrates the importance of an expanded differential diagnosis when confronted with a clinically atypical mass lesion.
肺孢子菌感染相关肿块临床上类似于恶性肿瘤（即假瘤）较为罕见，通常与卡氏肺孢子菌肺炎相关，发生于肺部。肺孢子菌小肠假瘤极其罕见，代表了一种不同寻常的播散性肺孢子菌感染形式。我们报告了一例小肠肺孢子菌假瘤病例，该患者患有获得性免疫缺陷综合征，同时合并巨细胞病毒感染，无肺部症状，也无已知的人类免疫缺陷病毒感染危险因素。该病例提示巨细胞病毒合并感染在播散性肺孢子菌感染中可能具有重要作用，也说明了在遇到临床表现不典型的肿块病变时，扩大鉴别诊断的重要性。
