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以肺孢子菌肺炎作为艾滋病界定疾病:一例说明范例转变的病例报告。

Apical Pneumocystis jiroveci as an AIDS defining illness: A case report illustrating a change in the paradigm.

作者信息

Pfeifer Kyle, Kalra Vivek, Adebowale Adeniran, Juthani-Mehta Manisha, Soo-Shin Myung

机构信息

Department of Radiology, Yale New Haven hospital, New Haven, CT, USA.

Department of Pathology, Yale New Haven hospital, New Haven, CT, USA.

出版信息

J Radiol Case Rep. 2014 Nov 30;8(11):15-24. doi: 10.3941/jrcr.v8i11.1772. eCollection 2014 Nov.

DOI:10.3941/jrcr.v8i11.1772
PMID:25926907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4394979/
Abstract

Pneumocystis jiroveci pneumonia is a common acquired immune deficiency syndrome defining illness. Pneumocystis jiroveci pneumonia is classically described as having symmetrical bilateral perihilar ground-glass opacities on chest radiographs. We present an "atypical" case of Pneumocystis jiroveci pneumonia presenting as symmetric biapical cystic spaces with relative sparing of the remainder of the lungs in a 22 year-old male, previously undiagnosed with acquired immune deficiency syndrome. Our case illustrates that formerly unusual presentations of Pneumocystis jiroveci pneumonia are becoming more common as acquired immune deficiency syndrome defining illnesses as more patients are being imaged with further imaging such as high resolution computed tomography.

摘要

耶氏肺孢子菌肺炎是一种常见的获得性免疫缺陷综合征界定疾病。经典的耶氏肺孢子菌肺炎在胸部X线片上表现为双侧对称性肺门周围磨玻璃影。我们报告一例“非典型”的耶氏肺孢子菌肺炎病例,该病例表现为一名22岁男性双侧肺尖部对称的囊腔,肺部其余部分相对 spared,该男性此前未被诊断为获得性免疫缺陷综合征。我们的病例表明,随着更多患者接受高分辨率计算机断层扫描等进一步成像检查,耶氏肺孢子菌肺炎以前不常见的表现作为获得性免疫缺陷综合征界定疾病正变得越来越普遍。 (注:spared这个词有误,可能是spared,结合语境推测是“ spared”,意为“ spared,幸免,未受影响” ,但原词错误不影响整体理解,故按照原文翻译,这里可以根据正确词汇灵活调整译文表述)

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本文引用的文献

1
Reversible cystic lesions of Pneumocystis jirovecii pneumonia.耶氏肺孢子菌肺炎的可逆性囊性病变
Am J Respir Crit Care Med. 2012 Mar 15;185(6):e7-8. doi: 10.1164/rccm.201103-0473IM.
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Multiple cystlike lung lesions in the adult.成人肺部的多发性囊样病变
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Molecular evidence of interhuman transmission in an outbreak of Pneumocystis jirovecii pneumonia among renal transplant recipients.肾移植受者中耶氏肺孢子菌肺炎暴发期间人际传播的分子证据
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Evolving health effects of Pneumocystis: one hundred years of progress in diagnosis and treatment.肺孢子菌不断演变的健康影响:诊断与治疗的百年进展
JAMA. 2009 Jun 24;301(24):2578-85. doi: 10.1001/jama.2009.880.
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Clin Infect Dis. 2009 Apr 15;48(8):1138-51. doi: 10.1086/597468.
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Unusual case of Pneumocystis jiroveci pneumonia during primary HIV infection.原发性人类免疫缺陷病毒感染期间发生的罕见耶氏肺孢子菌肺炎病例。
AIDS Read. 2008 Jun;18(6):313-7.
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Pneumocystis pneumonia in patients with HIV infection: clinical manifestations, laboratory findings, and radiological features.HIV感染患者的肺孢子菌肺炎:临床表现、实验室检查结果及影像学特征。
J Infect Chemother. 2007 Feb;13(1):1-7. doi: 10.1007/s10156-006-0484-5. Epub 2007 Feb 26.
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Emerg Infect Dis. 2004 Oct;10(10):1713-20. doi: 10.3201/eid1010.030985.