Linsen Sabine S, Reich Rudolf H, Teschke Marcus
Department of Prosthodontics, Preclinical Education, and Dental Materials Science, University Hospital Bonn, Germany.
J Oral Maxillofac Surg. 2012 Nov;70(11):2531-42. doi: 10.1016/j.joms.2012.06.193. Epub 2012 Aug 29.
Alloplastic total temporomandibular joint replacement (TJR) for end-stage disease, congenital disorders, and after ablative surgery has been shown improve function and to decrease pain. The purpose of this study was to evaluate the pain pressure threshold (PPT) and oral health-related quality of life (OHRQoL) in patients undergoing alloplastic TJR.
Subjects requiring TJR from May 2007 through February 2011 were enrolled in the study. The PPT and OHRQoL were measured preoperatively and 2, 6, and 12 months postoperatively. The primary predictor variable was postoperative time (preoperatively and 2, 6, and 12 months postoperatively). The primary outcome variables were the PPT and OHRQoL.
Seventeen subjects requiring TJR were enrolled in and completed the required 12-month follow-up. There was no difference in the PPT at any time point. There was a significant improvement in the OHRQoL domain of psychological discomfort (P = .04) at 12 months. Facial pain intensity, temporomandibular joint pain, mandibular function, and diet were also significantly improved at 12 months (P = .001).
Alloplastic TJR appears to decrease pain, improve function and diet, and decrease psychological discomfort.
对于终末期疾病、先天性疾病以及切除术后患者，异体全颞下颌关节置换术（TJR）已被证明可改善功能并减轻疼痛。本研究的目的是评估接受异体TJR患者的疼痛压力阈值（PPT）和口腔健康相关生活质量（OHRQoL）。
纳入2007年5月至2011年2月期间需要进行TJR的患者。在术前以及术后2、6和12个月测量PPT和OHRQoL。主要预测变量为术后时间（术前以及术后2、6和12个月）。主要结局变量为PPT和OHRQoL。
17名需要进行TJR的患者被纳入研究并完成了所需的12个月随访。在任何时间点，PPT均无差异。在12个月时，心理不适的OHRQoL领域有显著改善（P = 0.04）。面部疼痛强度、颞下颌关节疼痛、下颌功能和饮食在12个月时也有显著改善（P = 0.001）。
异体TJR似乎可减轻疼痛、改善功能和饮食，并减轻心理不适。
