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碳青霉烯类耐药肠杆菌科评分:一种床边评分,用于排除住院患者中碳青霉烯类耐药肠杆菌科感染。

The carbapenem-resistant Enterobacteriaceae score: a bedside score to rule out infection with carbapenem-resistant Enterobacteriaceae among hospitalized patients.

机构信息

Department of Pharmacy Practice, Wayne State University, Detroit, MI 48201, USA.

出版信息

Am J Infect Control. 2013 Feb;41(2):180-2. doi: 10.1016/j.ajic.2012.02.036. Epub 2012 Aug 30.

Abstract

Patients infected with carbapenem-resistant Enterobacteriaceae often experience delays in initiation of appropriate antimicrobial therapy and increased mortality. A score was developed to differentiate bloodstream infections caused by carbapenem-resistant Enterobacteriaceae (16 patients) versus extended-spectrum β-lactamase-producing Enterobacteriaceae (166 patients). A score of ≥ 32 demonstrated high area under the curve of 0.80 (95% confidence interval: 0.68-0.92) and a negative predictive value of 97%.

摘要

耐碳青霉烯类肠杆菌科细菌感染的患者通常在开始适当的抗菌治疗时会出现延迟,并增加死亡率。开发了一个评分系统来区分耐碳青霉烯类肠杆菌科细菌(16 例患者)与产超广谱β-内酰胺酶肠杆菌科细菌(166 例患者)引起的血流感染。评分≥32 时,曲线下面积的高值为 0.80(95%置信区间:0.68-0.92),阴性预测值为 97%。

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