Department of Neurology, Rambam Health Care Campus and Technion Faculty of Medicine, Haifa, Israel.
J Clin Neurosci. 2012 Nov;19(11):1593-4. doi: 10.1016/j.jocn.2012.03.019. Epub 2012 Aug 29.
Hypercoagulability is a condition predisposing to arterial or venous thrombosis and is associated frequently with malignancy. We present a rare acute ischemic stroke in a young patient that was the presenting feature for a newly diagnosed papillary carcinoma of the thyroid. Extensive vascular and hematological work-up was normal except for a large patent foramen ovale (PFO). This finding, along with the association of most vascular events with hypercoagulability being of venous origin, makes the mechanism of paradoxical embolism through the large PFO the probable cause of stroke in our patient.
高凝状态是一种易发生动脉或静脉血栓形成的病症，常与恶性肿瘤有关。我们报告了一例年轻患者的罕见急性缺血性脑卒中，其首发表现为新诊断的甲状腺乳头状癌。广泛的血管和血液学检查除了大的卵圆孔未闭（PFO）外均正常。这一发现，以及大多数与高凝状态相关的血管事件均源于静脉，使得通过大的 PFO 发生矛盾栓塞的机制成为导致我们患者卒中的可能原因。
