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短讯：北欧牛种内和种间的基因型推断。

Short communication: genotype imputation within and across Nordic cattle breeds.

机构信息

Centre for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, DK-8830 Tjele, Denmark.

出版信息

J Dairy Sci. 2012 Nov;95(11):6795-800. doi: 10.3168/jds.2012-5585. Epub 2012 Aug 29.

DOI:10.3168/jds.2012-5585
PMID:22939787
Abstract

This study investigated the accuracies of imputation from 50K genotypes to high-density genotypes for animals from the Danish, Swedish, or Finnish Red dairy cattle populations, using either a national, combined Red, or combined Red and Holstein reference population. Combining the Red populations increased the imputation accuracy for all 3 populations compared with using single-nationality references. Including Holstein animals in the reference further increased the imputation accuracy for Danish Red.

摘要

本研究调查了使用全国性、综合红牛或综合红牛和荷斯坦参考群体，从丹麦、瑞典或芬兰红牛奶牛群体的 50K 基因型向高密度基因型进行推断的准确性。与使用单一国家参考群体相比，组合红牛群体提高了所有 3 个群体的推断准确性。在参考群体中加入荷斯坦动物进一步提高了丹麦红牛的推断准确性。

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