中国上海丙型肝炎病毒基因型多样性。
Hepatitis C virus genotype diversity in Shanghai, China.
机构信息
Key Laboratory of Medical Molecular Virology (MOE/MOH) and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, People's Republic of China.
出版信息
Arch Virol. 2013 Jan;158(1):187-91. doi: 10.1007/s00705-012-1457-x. Epub 2012 Sep 2.
PMID:22941570
Abstract
We studied 67 hepatitis C virus (HCV) isolates from 64 hospitalized patients in Shanghai, China. Genotype 1 was prevalent, and genotypes 2, 3, 6 were found for the first time in Shanghai. A rare mixed infection with three subtypes (1a, 1b, 2a) was found. The complete genome sequence of a subtype 3b isolate was determined and analyzed.
摘要
我们研究了来自中国上海 64 名住院患者的 67 株丙型肝炎病毒 (HCV) 分离株。基因型 1 较为流行，同时在上海也首次发现了基因型 2、3、6。还发现了一例罕见的三种亚型（1a、1b、2a）混合感染。测定并分析了一株 3b 亚型分离株的全基因组序列。
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