影响拔毛癖发病的遗传因素。
The genetic factors influencing the development of trichotillomania.
作者信息
Chattopadhyay Koushik
机构信息
Nelson R. Mandela School of Medicine, University of Kwazulu-Natal, Durban, Republic of South Africa.
出版信息
J Genet. 2012 Aug;91(2):259-62. doi: 10.1007/s12041-011-0094-6.
PMID:22942103
Abstract
Trichotillomania (TTM), an obsessive-compulsive spectrum disorder (OCSD), is a psychiatric condition characterized by repetitive hair pulling. Evidence from family and twin studies suggest a heritable link of TTM. Functional polymorphisms in genes involved in neuronal pathways might influence the susceptibility to TTM. This review is an attempt to compile the genetic factors reported to modify the development of TTM.
摘要
拔毛癖（TTM）是一种强迫谱系障碍（OCSD），是一种以反复拔毛为特征的精神疾病。家族和双胞胎研究的证据表明TTM存在遗传联系。参与神经通路的基因中的功能多态性可能会影响患TTM的易感性。这篇综述旨在汇总据报道可影响TTM发病的遗传因素。
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