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530例患者的三尖瓣手术。早期和晚期事件的25年评估。

Tricuspid valve operations in 530 patients. Twenty-five-year assessment of early and late phase events.

作者信息

McGrath L B, Gonzalez-Lavin L, Bailey B M, Grunkemeier G L, Fernandez J, Laub G W

机构信息

Department of Surgery, Deborah Heart and Lung Center, Browns Mills, NJ 08015.

出版信息

J Thorac Cardiovasc Surg. 1990 Jan;99(1):124-33.

PMID:2294345
Abstract

From Jan. 1, 1961, through Dec. 31, 1987, 530 patients underwent an intracardiac operation that included a tricuspid valve procedure. The tricuspid valve was repaired in 351 patients (66%) and replaced in 179 (34%). Mean age was 56.9 years. Risk factors associated with tricuspid valve replacement included tricuspid stenosis (p = 0.02), jugular venous distention (p = 0.04), previous operation (p = 0.05), and angiographic severity of tricuspid valve incompetence (p less than 0.001). There were 78 hospital deaths (15%). Risk factors for hospital death included previous operation (p = 0.03), male gender (p = 0.03), hepatomegaly (p = 0.03), De Vega or Carpentier annuloplasty (repair group only), (p = 0.01), and older age at operation (p = 0.06). Ninety-eight percent of the patients were followed up. There were 185 late deaths (41%). The actuarial survival rate was 20% at 180 months. Risk factors for late death included male gender (p = 0.03), hepatomegaly (p = 0.04), and lack of postoperative warfarin therapy (p less than 0.001). Actuarial freedom from reoperation was 25.5% at 180 months. There was no difference in reoperation rates (p = 0.10) or survival (p = 0.42) whether the tricuspid valve had been repaired or replaced. We conclude that the requirement for surgical treatment of tricuspid valve insufficiency in patients with multivalvular disease constitutes a high risk group for cardiac surgery. Preoperative variables may predict the result of tricuspid valve replacement. Tricuspid valve replacement may be performed with the expectation of a low risk of valve-related events.

摘要

从1961年1月1日至1987年12月31日,530例患者接受了包括三尖瓣手术在内的心脏内手术。351例患者(66%)的三尖瓣得到修复,179例(34%)进行了置换。平均年龄为56.9岁。与三尖瓣置换相关的危险因素包括三尖瓣狭窄(p = 0.02)、颈静脉扩张(p = 0.04)、既往手术史(p = 0.05)以及三尖瓣关闭不全的血管造影严重程度(p < 0.001)。有78例医院死亡(15%)。医院死亡的危险因素包括既往手术史(p = 0.03)、男性(p = 0.03)、肝肿大(p = 0.03)、德维加或卡彭蒂埃瓣环成形术(仅修复组)(p = 0.01)以及手术时年龄较大(p = 0.06)。98%的患者得到随访。有185例晚期死亡(41%)。180个月时的精算生存率为20%。晚期死亡的危险因素包括男性(p = 0.03)、肝肿大(p = 0.04)以及术后未进行华法林治疗(p < 0.001)。180个月时再次手术的精算无再手术率为25.5%。无论三尖瓣是修复还是置换,再次手术率(p = 0.10)或生存率(p = 0.42)均无差异。我们得出结论,多瓣膜病患者三尖瓣关闭不全的手术治疗需求构成了心脏手术的高危组。术前变量可预测三尖瓣置换的结果。进行三尖瓣置换时可预期瓣膜相关事件的风险较低。

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