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电子径向和曲线内镜超声检查在胰腺恶性肿瘤检测中的比较

A comparison of electronic radial and curvilinear endoscopic ultrasonography in the detection of pancreatic malignant tumor.

作者信息

Kanazawa Keisuke, Imazu Hiroo, Mori Naoki, Ikeda Keiichi, Kakutani Hiroshi, Sumiyama Kazuki, Hino Shoryoku, Ang Tiing Leong, Omar Salem, Tajiri Hisao

机构信息

Department of Endoscopy, The Jikei University School of Medicine, Tokyo, Japan.

出版信息

Scand J Gastroenterol. 2012 Nov;47(11):1313-20. doi: 10.3109/00365521.2012.719930. Epub 2012 Sep 4.

DOI:10.3109/00365521.2012.719930
PMID:22943477
Abstract

OBJECTIVE

There is no comparative study of electronic radial endoscopic ultrasonography (ER-EUS) and electronic curvilinear EUS (EC-EUS). The aim of this study was to compare the accuracy of ER-EUS and EC-EUS for detecting pancreatic malignancies.

METHODS

This was a retrospective review of the patients who had EUS assessment from September 2008 to December 2011 for suspicious pancreatic tumors. Sensitivity, specificity, and area under the ROC curve to detect pancreatic malignancies were calculated and compared between the ER-EUS and EC-EUS cohort. The final diagnosis of pancreatic malignancy was based on pathology, or the consensus of patient's clinical course and multimodal imaging tests.

RESULTS

Two hundred twenty-one patients were included and divided into two cohorts: ER-EUS (n = 139) and EC-EUS (n = 82) cohorts. With propensity score matching method, 70 cases in each cohort were selected for the comparison. There was no significant difference in sensitivity, specificity, and area under the ROC curve to detect pancreatic malignancy between ER-EUS and EC-EUS cohort (88.5 vs. 100%, 88.6 vs. 90.9%, 0.8855 vs. 0.9545).

CONCLUSION

ER-EUS and EC-EUS provided similar accuracy for the detection of pancreatic malignancies. In view of similar diagnostic results of ER-EUS and EC-EUS for the detection of pancreatic malignancy, and the advantage of being able to perform FNA with EC-EUS, EC-EUS may be the preferred choice.

摘要

目的

目前尚无关于电子径向内镜超声检查(ER-EUS)和电子曲线超声内镜检查(EC-EUS)的对比研究。本研究旨在比较ER-EUS和EC-EUS检测胰腺恶性肿瘤的准确性。

方法

这是一项对2008年9月至2011年12月因胰腺肿瘤可疑而接受超声内镜检查的患者的回顾性研究。计算并比较ER-EUS组和EC-EUS组检测胰腺恶性肿瘤的敏感性、特异性和ROC曲线下面积。胰腺恶性肿瘤的最终诊断基于病理结果,或患者临床病程及多模态影像检查的共识。

结果

共纳入221例患者,分为两组:ER-EUS组(n = 139)和EC-EUS组(n = 82)。采用倾向评分匹配法,每组各选取70例进行比较。ER-EUS组和EC-EUS组在检测胰腺恶性肿瘤的敏感性、特异性和ROC曲线下面积方面无显著差异(88.5%对100%,88.6%对90.9%,0.8855对0.9545)。

结论

ER-EUS和EC-EUS在检测胰腺恶性肿瘤方面具有相似的准确性。鉴于ER-EUS和EC-EUS在检测胰腺恶性肿瘤方面诊断结果相似,且EC-EUS具有能够进行细针穿刺抽吸的优势,EC-EUS可能是首选。

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