Centre for Population Health, Burnet Institute, Melbourne, Australia.
Drug Alcohol Rev. 2013 Mar;32(2):208-10. doi: 10.1111/j.1465-3362.2012.00502.x. Epub 2012 Sep 3.
Accurate knowledge of individual hepatitis C virus (HCV) status is an important component of comprehensive health services for people who inject drugs (PWID). In this paper we compare the perceived HCV status of PWID in a longitudinal cohort study with their actual status, as verified by HCV-RNA testing.
Participants who consented to blood testing at first follow up (352/688) were included. Self-reported HCV status (positive/negative/don't know), was compared with serology test results for participants.
In comparing self-report with HCV-RNA results, 274 of 352 participants had valid serology and self-report results; of these, 220 (80%) accurately reported their HCV status.
The findings of this study suggest that large proportions of PWID know their true HCV infection status, but the discordant participants represent potential HCV infection risks. Despite the majority of participants displaying concordance, this study reinforces the need for regular blood testing and the giving of accurate, practical and comprehensive HCV result information.
准确了解个体丙型肝炎病毒 (HCV) 状况是为注射吸毒者 (PWID) 提供全面健康服务的重要组成部分。在本文中,我们将通过 HCV-RNA 检测来验证,比较纵向队列研究中 PWID 对自身 HCV 状况的感知与实际状况。
纳入了首次随访时同意进行血液检测的参与者(688 名中的 352 名)。比较参与者的自我报告 HCV 状况(阳性/阴性/不知道)与血清学检测结果。
在将自我报告与 HCV-RNA 结果进行比较时,352 名参与者中有 274 名具有有效的血清学和自我报告结果;其中,220 名(80%)准确报告了他们的 HCV 状况。
这项研究的结果表明,很大一部分 PWID 了解自己的真实 HCV 感染状况,但不一致的参与者代表了潜在的 HCV 感染风险。尽管大多数参与者表现出一致性,但这项研究强调了定期进行血液检测以及提供准确、实际和全面的 HCV 结果信息的必要性。