Krans Elizabeth E, Rothenberger Scott D, Morrison Penelope K, Park Seo Young, Klocke Leah C, Turocy Mary J, Zickmund Susan
Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Magee-Womens Research Institute, 3380 Boulevard of the Allies, Suite 323, Pittsburgh, PA, 15213, USA.
Matern Child Health J. 2018 Aug;22(8):1208-1216. doi: 10.1007/s10995-018-2506-1.
Objectives To evaluate Hepatitis C virus (HCV) knowledge and awareness among pregnant women with opioid use disorder (OUD). Methods From May through November 2015, a one-time survey was distributed to a convenience sample of pregnant women with OUD to assess their knowledge and awareness of (a) risk factors for HCV infection, (b) HCV transmission prevention strategies, (c) hepatotoxic risk reduction and (d) perinatal transmission and neonatal implications of HCV infection. Chi square and Fisher's exact tests were used to compare demographic characteristics and HCV knowledge between participants who were HCV positive and negative. Results Of 179 pregnant women with OUD approached, 169 (94%) completed the survey. Of these, 153 (90.5%) reported at least one risk factor for HCV infection, 85 (50.3%) were HCV positive and 38 (44.7%) of HCV positive women were diagnosed with HCV for the first time during pregnancy. When HCV knowledge was evaluated, 114 (66.7%) responded that sharing eating utensils could transmit HCV, 69 (55.0%) responded that there is a vaccine to prevent HCV and 56 (32.7%) did not identify intranasal drug use as a risk factor for HCV transmission. Among HCV positive women, 61 (71.8%) associated breastfeeding with an increased risk for HCV transmission, 33 (38.1%) failed to identify the importance of pediatric follow-up for HCV-exposed children and 16 (18.8%) perceived the risk of HCV vertical transmission as "likely" or "very likely." Conclusions for Practice Gaps in HCV knowledge exist among a rapidly growing population of pregnant women with OUD. Healthcare providers have a unique opportunity to provide HCV education and counseling during pregnancy.
目的 评估患有阿片类物质使用障碍（OUD）的孕妇对丙型肝炎病毒（HCV）的知识和认知。方法 2015年5月至11月，对患有OUD的孕妇便利样本进行了一次性调查，以评估她们对以下方面的知识和认知：（a）HCV感染的危险因素，（b）HCV传播预防策略，（c）肝毒性风险降低，以及（d）HCV感染的围产期传播和对新生儿的影响。采用卡方检验和费舍尔精确检验比较HCV阳性和阴性参与者的人口统计学特征和HCV知识。结果 在179名接触到的患有OUD的孕妇中，169名（94%）完成了调查。其中，153名（90.5%）报告至少有一项HCV感染危险因素，85名（50.3%）HCV呈阳性，38名（44.7%）HCV阳性女性在孕期首次被诊断出HCV感染。在评估HCV知识时，114名（66.7%）回答共用餐具可传播HCV，69名（55.0%）回答有预防HCV的疫苗，56名（32.7%）未将鼻内吸毒识别为HCV传播的危险因素。在HCV阳性女性中，61名（71.8%）认为母乳喂养会增加HCV传播风险，33名（38.1%）未认识到对HCV暴露儿童进行儿科随访的重要性，16名（18.8%）认为HCV垂直传播风险为“可能”或“非常可能”。实践结论 在快速增长的患有OUD的孕妇群体中，存在HCV知识方面的差距。医疗保健提供者在孕期有独特的机会提供HCV教育和咨询。
