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[前庭神经鞘瘤:第一部分:流行病学与诊断]

[Vestibular schwannoma: Part I: epidemiology and diagnostics].

作者信息

Hassepass F, Bulla S B, Aschendorff A, Maier W

机构信息

Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde, Albert-Ludwigs-Universität, Freiburg, Deutschland.

出版信息

HNO. 2012 Sep;60(9):837-44; quiz 845-6. doi: 10.1007/s00106-012-2533-y.

Abstract

Vestibular schwannoma is with 80% the most frequent of all tumors of the cerebellopontine angle. Usually, this benign, neuroectodermal, mostly unilateral occurring tumor is called acoustic neuroma, although it develops from the Schwann cells of the nerve sheath of the eighth cranial nerve. The tumor is localized in the meatus acusticus internus in the majority of cases. The most common initial symptom is a unilateral or, at least, asymmetric hearing loss. Other symptoms may include tinnitus and feeling of insecurity or vertigo, but adjacent cranial nerves may also be affected. Besides clinical and apparatus-based (neuro-)otological diagnostics, MRI imaging has established itself as the gold standard with a sensitivity and specificity of up to 100%.

摘要

前庭神经鞘瘤占桥小脑角区所有肿瘤的80%,是最常见的。通常,这种良性的神经外胚层肿瘤大多单侧发生,虽起源于第八颅神经神经鞘的施万细胞,但通常被称为听神经瘤。大多数情况下,肿瘤位于内耳道。最常见的初始症状是单侧或至少不对称性听力丧失。其他症状可能包括耳鸣、不安全感或眩晕,但相邻的颅神经也可能受到影响。除了临床和基于仪器的(神经)耳科诊断外,MRI成像已成为金标准,其敏感性和特异性高达100%。

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