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[前庭神经鞘瘤——基线与进展诊断]

[Vestibular schwannomas - baseline and progress diagnostics].

作者信息

Kemper Max, Paliege Katja, Zahnert Thomas

机构信息

Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Carl Gustav Carus, Dresden.

出版信息

Laryngorhinootologie. 2022 Jun;101(6):518-538. doi: 10.1055/a-1739-6662. Epub 2022 Jun 20.

Abstract

Vestibular (vestibulocochlear) schwannomas are rare, benign schwannomas of the cerebellopontine angle, the internal auditory canal, or the inner ear. They can occur with or without clinical symptoms. The most common symptoms are unilateral or side-differentiated hearing loss with or without tinnitus and balance disorders. Initial symptomatology is nonspecific in the basic functional diagnosis, raising the question of when a hearing or balance disorder should be thought of as a differential diagnosis of vestibular schwannoma and what diagnostic pathway is appropriate. This concerns not only the confirmation of the diagnosis and the recording of all dysfunctions of the involved cranial nerves in the initial basic diagnostics, but also the procedure in the course and follow-up diagnostics - especially in patients who are subject to an observation strategy. Today, imaging alone is no longer sufficient for differentiated and individualized patient counseling. Due to the increasing detection of smaller tumors on MRI and the growing proportion of nearly asymptomatic patients, a shift in thinking from pure imaging monitoring to a detailed analysis of auditory and vestibular function is timely. In this educational article, diagnostic pathways for a sufficient patient consultation will be compiled. Ultimately, functional examination techniques from follow-up and progression diagnostics will also be included.

摘要

前庭(前庭蜗)神经鞘瘤是一种罕见的、位于桥小脑角、内耳道或内耳的良性神经鞘瘤。它们可伴有或不伴有临床症状。最常见的症状是单侧或双侧有差异的听力损失,伴有或不伴有耳鸣以及平衡障碍。在基本功能诊断中,初始症状不具有特异性,这就引发了一个问题:何时应将听力或平衡障碍视为前庭神经鞘瘤的鉴别诊断,以及何种诊断途径是合适的。这不仅涉及在初始基本诊断中确诊以及记录受累颅神经的所有功能障碍,还涉及病程及随访诊断中的程序——尤其是对于采用观察策略的患者。如今,仅靠影像学检查已不足以进行差异化和个性化的患者咨询。由于磁共振成像(MRI)上越来越多地检测到较小的肿瘤,以及几乎无症状患者的比例不断增加,从单纯的影像学监测转向对听觉和前庭功能进行详细分析的思维转变是适时的。在这篇教育性文章中,将汇编出足以进行患者咨询的诊断途径。最终,还将纳入随访和病情进展诊断中的功能检查技术。

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