South Essex Partnership University Foundation Trust, Bedford Hospital, Bedford, UK.
Psychiatr Danub. 2012 Sep;24 Suppl 1:S28-35.
We compare the reported side effects of medication from the trials of prodromal psychosis treatment. We note that the side effects of antipsychotics are those described in the usual pharmacology of these substances and that the severity of side effects are dependent on dosage, with more side effects at higher doses. We report on the search for alternative compounds for the treatment of prodromal psychosis. Omega fatty acids and Cognitive Behavioural Therapy are certainly good adjuvant treatments for suspected prodromal psychosis. With further evidence they may be considered appropriate to use as monotherapy, particularly in the early prodrome. Treatment of prodromal psychosis continues to present a number of risks; therefore the decision to treat ultimately must depend on the symptoms presented by the individual.
我们比较了前驱期精神病治疗试验报告的药物副作用。我们注意到，抗精神病药物的副作用是这些物质通常药理学中描述的副作用，副作用的严重程度取决于剂量，剂量越高，副作用越多。我们报告了寻找治疗前驱期精神病的替代化合物的情况。欧米伽脂肪酸和认知行为疗法肯定是前驱期精神病疑似患者的良好辅助治疗方法。随着进一步的证据，它们可能被认为是合适的单药治疗，特别是在前驱期早期。前驱期精神病的治疗仍然存在一些风险；因此，治疗的决定最终必须取决于个体的症状。
