Department of Psychiatry, Medical University of Gdańsk, Gdańsk, Poland.
Psychiatr Danub. 2012 Sep;24 Suppl 1:S41-3.
Impulsivity is the neurophysiologically based inability to confirm behaviour to its context or consequences. Overimpulsiveness characterizes many mental disorders and poses an important clinical dilemma. Although the relationship between mood disorders and impulsivity has been well studied the relationship between anxiety and impulsivity is controversial and not well explored. Some studies hypothesise that patients with the diagnosis of panic disorders are characterised by higher levels of impulsivity as a trait as compared to healthy individuals. The aim of this study was to assess cognitive correlates in panic disorder as related to impulsivity measures.
Within the preliminary studies four patients diagnosed with panic disorder (DSM-IV-TR) were studied. The severity measure was the Panic and Agoraphobia Scale. The experimental group comprised of psychotropic drug naive patients. Impulsiveness was evaluated with the Barrat Impulsiveness Scale - 11th version (BIS-11). To asses cognitive functions we used CANTAB (Cambridge Neuropsychological Test Automated Battery).
BIS-11 scores observed in the group of psychotropic drug naive patients with panic disorder were higher than the adjusted average for the population and correlated with the number of mistakes in CANTAB (Spatial Working Memory Test); rs=0.949; p=0.0513.
The preliminary findings indicate a correlation between impulsivity and cognitive deficits in panic disorder in psychotropic drug naive patients.
冲动是一种神经生理学基础上的无法确认行为与其背景或后果之间关系的能力。过度冲动是许多精神障碍的特征，也是一个重要的临床难题。尽管心境障碍与冲动之间的关系已经得到了很好的研究，但焦虑与冲动之间的关系仍存在争议，尚未得到充分探索。一些研究假设，与健康个体相比，被诊断为恐慌症的患者具有更高水平的冲动特质。本研究旨在评估恐慌症患者的认知相关性与冲动性测量之间的关系。
在初步研究中，对四名被诊断为恐慌症（DSM-IV-TR）的患者进行了研究。严重程度的测量是恐慌和广场恐惧症量表。实验组由未经精神药物治疗的患者组成。冲动性用巴瑞特冲动量表-第 11 版（BIS-11）进行评估。为了评估认知功能，我们使用了剑桥神经心理学测试自动化电池（CANTAB）。
未经精神药物治疗的恐慌症患者组的 BIS-11 评分高于人群的平均水平，并与 CANTAB（空间工作记忆测试）中的错误数量相关；rs=0.949;p=0.0513。
初步发现表明，未经精神药物治疗的恐慌症患者的冲动性与认知缺陷之间存在相关性。
