Department of Academic Rheumatology, Division of Immunology, Inflammatory & Infectious Disease, School of Medicine, Guy's Campus, King's College London, London SE1 1UL, UK.
Immunotherapy. 2012 Aug;4(8):773-5. doi: 10.2217/imt.12.78.
The field of heat-shock protein (HSP) research has been revitalized when extracellular HSPs were reported in the literature in the 1990s. Emerging findings suggest that HSPs can perform a wide variety of biological functions, more than their traditional role as molecular chaperones. With prominent speakers from various HSP fields, the 1(st) Heat Shock Protein - Multiple Roles in Inflammation, Vaccination and Homeostasis Conference covered topics on intracellular and extracellular HSPs along with the role of bacterial and self-HSPs. This conference, organized by Euroscicon, brought together more than 20 delegates from industry and academia for a lively discussion of the current state of HSP research.
当 20 世纪 90 年代文献中报道细胞外热休克蛋白 (HSP) 时,HSP 研究领域重新焕发生机。新出现的研究结果表明,HSP 可以发挥多种生物学功能,而不仅仅是其作为分子伴侣的传统作用。本次由 Euroscicon 组织的第一届 HSP-炎症、疫苗接种和动态平衡中的多种作用会议汇集了来自各个 HSP 领域的知名演讲者,涵盖了细胞内和细胞外 HSP 以及细菌和自身 HSP 的作用等主题。该会议召集了 20 多名来自工业界和学术界的代表,就 HSP 研究的现状进行了热烈的讨论。