Department of Radiation Oncology, Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
J Xray Sci Technol. 2012;20(3):317-29. doi: 10.3233/XST-2012-0340.
A Monte Carlo application is developed to investigate the yields of positron-emitting nuclei (PEN) used for proton and carbon ion range verification techniques using the GEANT4 Toolkit. A base physics list was constructed and used to simulate incident proton and carbon ions onto a PMMA or water phantom using pencil like beams. In each simulation the total yields of PEN are counted and both the PEN and their associated positron depth-distributions were recorded and compared to the incident radiation's Bragg Peak. Alterations to the physics lists are then performed to investigate the PEN yields dependence on the choice of physics list. In our study, we conclude that the yields of PEN can be estimated using the physics list presented here for range verification of incident proton and carbon ions.
开发了一个蒙特卡罗应用程序，使用 GEANT4 工具包研究用于质子和碳离子射程验证技术的正电子发射核（PEN）的产额。构建了一个基础物理列表，并使用铅笔束模拟入射质子和碳离子到 PMMA 或水模体上。在每个模拟中，计算 PEN 的总产额，并记录 PEN 及其相关正电子深度分布，并与入射辐射的布拉格峰进行比较。然后对物理列表进行修改，以研究 PEN 产额对物理列表选择的依赖性。在我们的研究中，我们得出结论，使用这里提出的物理列表可以估计用于入射质子和碳离子射程验证的 PEN 产额。
