Yun Hyun Don, Ershler William B
Department of Medicine, Harbor Hospital Center, Baltimore, Maryland, USA.
BMJ Case Rep. 2012 Sep 3;2012:bcr2012006480. doi: 10.1136/bcr-2012-006480.
Superior vena cava (SVC) syndrome is an uncommon complication of malignant disease caused by the obstruction of venous blood flow in the SVC. When present, a diagnosis of lung cancer or lymphoma will be made in approximately 95% of cases. Although other malignant diseases are occasionally associated with SVC, its occurrence in patients with prostate cancer is rare. We present a case of a patient presenting with SVC obstruction who was subsequently diagnosed with prostate adenocarcinoma. The patient has been successfully treated with GnRH agonist. This case reflects the importance of a full clinical assessment and pathological confirmation of suspected tumour prior to treatment.
上腔静脉（SVC）综合征是恶性疾病的一种罕见并发症，由上腔静脉内静脉血流阻塞引起。出现该综合征时，约95%的病例会被诊断为肺癌或淋巴瘤。虽然其他恶性疾病偶尔也与上腔静脉综合征有关，但其在前列腺癌患者中很少发生。我们报告一例出现上腔静脉阻塞的患者，该患者随后被诊断为前列腺腺癌。该患者已成功接受促性腺激素释放激素（GnRH）激动剂治疗。此病例反映了在治疗前对疑似肿瘤进行全面临床评估和病理确认的重要性。
