Grover Sandeep, Shah Ruchita, Kr Aarya
Turk Psikiyatri Derg. 2012 Fall;23(3):189-92.
Data from Western countries suggest that delirium is associated with a high rate of mortality; however, the mortality rate in patients with delirium in India has not been studied. The aim of this study is to determine the mortality rate among a group of hospitalized patients with delirium 6 months after being diagnosed with delirium.
The study included 97 patients with delirium that were evaluated by the consultation-liaison psychiatric team. Informed consent was provided by the patients' caregivers. The patients were rated according to the Delirium Rating Scale-Revised 98 (DRS-R-98) and Delirium Motor Subtype Scale, and the etiology of delirium was recorded using a structured format.
Mean age of the patients was 47.14 ± 18.10 years and mean duration of formal education was 8.35 ± 5.63 years. Most of the patients were male (n = 69, 71.13%) and had hospital-emergent delirium (n = 68, 70.10%). Mean duration of delirium was 4.15 ± 5.71 d at the time of assessment and mean DRS-R-98 score was 30.71 ± 4.82. Among the 97 patients, 12 (12.1%) died during their hospital stay- a higher mortality rate than that observed in other patients referred for consultation-liaison psychiatric services that were diagnosed with psychiatric disorders other than delirium (4.43%) or not diagnosed with a psychiatric disorder (no deaths) during the same time period. The mortality rate in patients with delirium was also significantly higher than that seen among all other hospital admissions during the study period (6.79%; 2119 deaths among 31,190 admissions; chi-square value: 4.73; P = 0.02). Mortality rate in patient's with delirium at 6 month follow-up was 27.83%.
Delirium in hospitalized patients is associated with a high mortality rate.
西方国家的数据表明,谵妄与高死亡率相关;然而,印度谵妄患者的死亡率尚未得到研究。本研究的目的是确定一组住院谵妄患者在被诊断为谵妄6个月后的死亡率。
本研究纳入了97例由会诊联络精神科团队评估的谵妄患者。患者的照料者提供了知情同意书。根据谵妄评定量表修订版98(DRS-R-98)和谵妄运动亚型量表对患者进行评分,并使用结构化格式记录谵妄的病因。
患者的平均年龄为47.14±18.10岁,平均正规教育年限为8.35±5.63年。大多数患者为男性(n = 69,71.13%),且患有医院突发谵妄(n = 68,70.10%)。评估时谵妄的平均持续时间为4.15±5.71天,DRS-R-98平均评分为30.71±4.82。在这97例患者中,12例(12.1%)在住院期间死亡——这一死亡率高于同期因其他精神障碍而非谵妄被转诊至会诊联络精神科服务的患者(4.43%)或未被诊断为精神障碍的患者(无死亡)。谵妄患者的死亡率也显著高于研究期间所有其他住院患者(6.79%;31190例住院患者中有2119例死亡;卡方值:4.73;P = 0.02)。6个月随访时谵妄患者的死亡率为27.83%。
住院患者的谵妄与高死亡率相关。