Foulkes G D, Johnson C E, Katner H P
Department of Surgery, Mercer University School of Medicine, Macon, Georgia.
Clin Orthop Relat Res. 1990 Feb(251):246-8.
The diagnosis of acute anaerobic osteomyelitis was made in a 57-year-old hypertensive diabetic woman complaining of groin pain and fever. Roentgenograms and computed tomography demonstrated intraosseous gas in the right femoral head and surrounding soft tissue. Cultures obtained from open biopsy were positive for the anaerobic gram-negative bacillus Fusobacterium necrophorum, a normal inhabitant of the mouth, bowel, and urogenital tract. The patient responded to an antibiotic regimen of metronidazole combined with initial debridement and drainage, followed by resection of the femoral head (Girdle-stone arthroplasty). The hospital course was complicated by fungal and pseudomonal superinfection. The patient was afebrile and ambulatory at discharge two months after admission. A case of Fusobacterium necrophorum osteomyelitis causing intraosseous gas seems not to have been previously reported in the literature.
一名57岁患有高血压和糖尿病的女性,因腹股沟疼痛和发热就诊,被诊断为急性厌氧性骨髓炎。X线片和计算机断层扫描显示右股骨头和周围软组织内有骨内气体。开放活检获取的培养物对厌氧革兰氏阴性杆菌坏死梭杆菌呈阳性,该菌是口腔、肠道和泌尿生殖道的正常寄居菌。患者对甲硝唑联合初始清创引流的抗生素治疗方案有反应,随后进行了股骨头切除术(Girdle-stone关节成形术)。住院过程中出现了真菌和假单胞菌二重感染的并发症。入院两个月后出院时,患者体温正常且可走动。文献中似乎此前未报道过由坏死梭杆菌骨髓炎导致骨内气体的病例。