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从喉咙痛到重症监护病房:勒米尔综合征

From a sore throat to the intensive care unit: the Lemierre syndrome.

作者信息

Hochmair Maximilian, Valipour Arschang, Oschatz Elisabeth, Hollaus Peter, Huber Monika, Chris Burghuber Otto

机构信息

Department of Respiratory and Critical Care Medicine, Otto-Wagner Hospital, Vienna, Austria.

出版信息

Wien Klin Wochenschr. 2006 May;118(7-8):243-6. doi: 10.1007/s00508-006-0571-8.

Abstract

Lemierre syndrome is characterized by an acute oropharyngeal infection, suppurative thrombophlebitis of the internal jugular vein and metastatic infections. The infection is usually caused by Fusobacterium necrophorum. We report on a 19-year-old male patient who was admitted with a five-day history of fever, sore throat and progressive dyspnea. Computed tomography of the neck and chest revealed a parapharyngeal abscess, jugular vein thrombosis, descending necrotizing mediastinitis and multiple areas of bilateral consolidation and cavitations within the lungs. Fusobacterium necrophorum was identified in the blood culture. Early combined abscess drainage with neck and chest incisions, together with broad spectrum intravenous antibiotic treatment and medical management in an intensive care unit resulted in a good clinical outcome.

摘要

勒米尔综合征的特征为急性口咽感染、颈内静脉化脓性血栓性静脉炎及转移性感染。感染通常由坏死梭杆菌引起。我们报告一名19岁男性患者,因发热、咽痛及进行性呼吸困难5天入院。颈部和胸部计算机断层扫描显示咽旁脓肿、颈静脉血栓形成、下行性坏死性纵隔炎以及肺部双侧多个实变和空洞区域。血培养中鉴定出坏死梭杆菌。早期联合颈部和胸部切口进行脓肿引流,同时给予广谱静脉抗生素治疗并在重症监护病房进行医疗管理,取得了良好的临床效果。

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