University of Lorraine, UFR STAPS, Villers-lès-Nancy, France.
Laryngoscope. 2012 Oct;122(10):2285-90. doi: 10.1002/lary.23497. Epub 2012 Sep 5.
OBJECTIVES/HYPOTHESIS: To evaluate the age-related effects of vestibular schwannoma (VS) on postural control and whether the postoperative postural strategies differ according to age.
Longitudinal, transversal study.
Forty-seven VS patients were split into three groups according to age (group I, 14 patients aged from 30 to 44 years; group II, 21 patients aged from 45 to 59 years; and group III, 12 patients aged from 60 to 75 years). All patients underwent vestibular and posturographic testing shortly before as well as 8 days and 3 months after surgical tumor removal.
Vestibular and postural performance followed a classical time course with degradation just after surgery and recovery 3 months after surgery, whatever the age group. However, in the elderly the improvement of postural performances compared to preoperatively was more important, especially in conflicting situations.
Despite of age-related decline in postural control and cognitive processes, neuroplasticity allowed not only a recovery but even an improvement of balance after surgical VS removal in the elderly. This study highlights the interest of VS surgery even at a more advanced age.
目的/假设：评估前庭神经鞘瘤（VS）对姿势控制的年龄相关影响，以及术后的姿势策略是否因年龄而异。
纵向、横向研究。
根据年龄将 47 名 VS 患者分为三组（I 组，14 名年龄在 30 至 44 岁的患者；II 组，21 名年龄在 45 至 59 岁的患者；III 组，12 名年龄在 60 至 75 岁的患者）。所有患者均在手术切除肿瘤前、术后 8 天和 3 个月进行前庭和姿势测试。
无论年龄组如何，前庭和姿势表现都遵循经典的时间过程，即术后即刻下降，3 个月后恢复。然而，与术前相比，老年人的姿势表现改善更为明显，尤其是在冲突情况下。
尽管与年龄相关的姿势控制和认知过程下降，但神经可塑性不仅允许在老年人中手术后 VS 切除后恢复，甚至可以改善平衡。这项研究强调了即使在年龄较大时进行 VS 手术的重要性。
