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韦格纳肉芽肿伴广泛骨异常,酷似真菌性鼻窦炎。

Wegener's granulomatosis with extensive bone abnormalities mimicking fungal sinusitis.

作者信息

Kodama Satoru, Nomi Nozomi, Suzuki Masashi

机构信息

Department of Otolaryngology, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hazama-Machi, Oita, Yufu 879-5593, Japan.

出版信息

Case Rep Otolaryngol. 2012;2012:103403. doi: 10.1155/2012/103403. Epub 2012 Jun 26.

Abstract

Abnormalities of the underlying bone of the paranasal sinuses have sometimes been shown in Wegener's granulomatosis (WG). We describe an interesting case of WG with extensive bone abnormalities in the sinuses mimicking fungal sinusitis. A 30-year-old woman presented with intermittent unilateral epistaxis. Biopsy was performed for the granulation tissue in the right nasal cavity, and she was diagnosed as having WG. Computed tomography (CT) revealed a ring-like calcification, mimicking a fungus ball, in the right maxillary sinus. Endoscopic sinus surgery was performed to confirm the diagnosis. A spherical bony structure, surrounded by granulation tissue, was identified in the maxillary sinus. The wall of the "bony ball" was fragile, like an egg shell. No fungus was found in the sinus. Thus, the extensive bone abnormalities were due to WG.

摘要

鼻窦的基础骨异常有时在韦格纳肉芽肿病(WG)中可见。我们描述了一例有趣的WG病例,其鼻窦存在广泛的骨异常,酷似真菌性鼻窦炎。一名30岁女性出现间歇性单侧鼻出血。对右侧鼻腔的肉芽组织进行了活检,她被诊断为患有WG。计算机断层扫描(CT)显示右侧上颌窦有环状钙化,类似真菌球。进行了鼻内镜鼻窦手术以确诊。在上颌窦中发现了一个被肉芽组织包围的球形骨质结构。“骨球”的壁很脆弱,像蛋壳一样。鼻窦内未发现真菌。因此,广泛的骨异常是由WG引起的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97db/3420613/9bb400444ce6/CRIM.OTOLARYNGOLOGY2012-103403.001.jpg

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