Section of Occupational Medicine, Department of Internal Medicine, Geriatrics and Nephrology, University of Bologna, Bologna, Italy.
Saf Health Work. 2012 Mar;3(1):52-7. doi: 10.5491/SHAW.2012.3.1.52. Epub 2012 Mar 8.
Lifting heavy weights involves the Valsalva manoeuvre, which leads to intraocular pressure spikes. We used data from a case-control study to further investigate the hypothesis that occupational lifting is a risk factor for retinal detachment.
The study population included 48 cases (patients operated for retinal detachment) and 84 controls (outpatients attending an eye clinic). The odds ratios (OR) of idiopathic retinal detachment were estimated with a logistic regression model (adjusted for age, sex and body mass index). Three indexes were used to examine exposure to lifting; 1) maximum load lifted, 2) average weekly lifting, 3) lifelong cumulative lifting.
For all indexes, the most exposed subjects showed an increased risk of retinal detachment compared with the unexposed (index 1: OR 3.57, 95% confidence interval [CI] 1.21-10.48; index 2: OR 3.24, 95% CI 1.32-7.97; index 3: OR 2.23, 95% CI 1.27-8.74) and dose-response relationships were apparent.
These results reinforce the hypothesis that heavy occupational lifting may be a relevant risk factor for retinal detachment.
举重会导致瓦尔萨尔瓦动作，从而导致眼压飙升。我们使用病例对照研究的数据进一步验证了这样一种假设，即职业性举重是视网膜脱离的一个危险因素。
研究人群包括 48 例（因视网膜脱离而行手术的患者）和 84 例对照（眼科门诊患者）。使用逻辑回归模型（调整年龄、性别和体重指数）估计特发性视网膜脱离的比值比（OR）。使用三个指标来检查举重的暴露情况：1）最大举重负荷，2）平均每周举重，3）终生累积举重。
对于所有指标，与未暴露者相比，暴露程度最高的受试者发生视网膜脱离的风险增加（指标 1：OR 3.57，95%置信区间 [CI] 1.21-10.48；指标 2：OR 3.24，95% CI 1.32-7.97；指标 3：OR 2.23，95% CI 1.27-8.74），且呈现明显的剂量-反应关系。
这些结果进一步证实了这样一种假设，即繁重的职业性举重可能是视网膜脱离的一个相关危险因素。
