Section of Cardiovascular Diseases, Department of Experimental and Applied Medicine, University of Study of Brescia, Brescia, Italy.
Cardiovasc Ther. 2013 Feb;31(1):27-31. doi: 10.1111/j.1755-5922.2012.00311.x.
Organic nitrates remain among the oldest and most commonly employed drugs in cardiology. Although, in most cases, their use in acute and chronic heart failure is based on clinical practice, only a few clinical trials have been conducted to evaluate their use in acute and chronic heart failure, most of which compare them with other drugs to evaluate differing endpoints. The purpose of this review is to examine the various trials that have evaluated the use of nitrates in acute and chronic heart failure.
有机硝酸盐仍然是心脏病学中最古老和最常用的药物之一。尽管在大多数情况下，它们在急性和慢性心力衰竭中的使用是基于临床实践，但只有少数临床试验评估了它们在急性和慢性心力衰竭中的使用，其中大多数将它们与其他药物进行比较以评估不同的终点。本综述的目的是检查评估硝酸盐在急性和慢性心力衰竭中的使用的各种试验。
