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侧支循环的力量:一例无症状的左主干冠状动脉慢性完全闭塞病例

The power of collateral circulation: a case of asymptomatic chronic total occlusion of the left main coronary artery.

作者信息

Saraon Tajinderpal, Chadow Hal L, Castillo Ricardo

机构信息

Division of Cardiology, Department of Medicine, Brookdale University Hospital and Medical Center, Brooklyn, NY 11212 USA.

出版信息

J Invasive Cardiol. 2012 Sep;24(9):E196-8.

Abstract

Total occlusion of the left main coronary artery predominantly presents with recurrent angina or myocardial infarction. Long-term survival and myocardial function depends on the well-developed right to left collaterals. We report a case of a 46-year-old man who was referred because of incidental finding of low ejection fraction during work-up for syncope 5 months prior. The patient denied any recurrence or any other symptom after that episode and claimed an unchanged exercise capacity. He had hypertension, hyperlipidemia, and history of 15-pack/year smoking. Except for class II morbid obesity, he had completely normal vital signs, physical examination, and lab tests on admission. The echocardiogram was suggestive of previous anterior wall myocardial infarction and demonstrated a low left ventricle ejection fraction with diffuse hypokinesis of the left ventricle. The patient underwent cardiac catheterization, which revealed total occlusion of the left main coronary artery, dominant right coronary artery with a 95% stenosis in the proximal segment, and collaterals from the right to the left coronary arteries. The patient was immediately referred for coronary artery bypass surgery. This case demonstrates the power of collateral circulation in protecting the patient from symptoms and death despite total occlusion of the left main coronary artery and severe stenosis of the proximal right coronary artery.

摘要

左主干冠状动脉完全闭塞主要表现为反复心绞痛或心肌梗死。长期生存及心肌功能取决于发育良好的右向左侧支循环。我们报告一例46岁男性患者,其因5个月前晕厥检查时偶然发现射血分数降低而前来就诊。该患者在那次发作后否认有任何复发或其他症状,并声称运动能力未变。他患有高血压、高脂血症,有15包/年的吸烟史。入院时,除II级病态肥胖外,他的生命体征、体格检查及实验室检查完全正常。超声心动图提示既往有前壁心肌梗死,显示左心室射血分数降低,左心室弥漫性运动减弱。患者接受了心导管检查,结果显示左主干冠状动脉完全闭塞,右冠状动脉优势型,近端节段有95%的狭窄,以及从右冠状动脉到左冠状动脉的侧支循环。该患者立即被转诊接受冠状动脉搭桥手术。本病例表明,尽管左主干冠状动脉完全闭塞且右冠状动脉近端严重狭窄,但侧支循环仍有能力保护患者免受症状困扰及死亡威胁。

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