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早发性脊柱侧弯:现代治疗方法与结果

Early onset scoliosis: modern treatment and results.

作者信息

Tis John E, Karlin Lawrence I, Akbarnia Behrooz A, Blakemore Laurel C, Thompson George H, McCarthy Richard E, Tello Carlos A, Mendelow Michael J, Southern Edward P

机构信息

Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Bloomberg Children's Center, Baltimore, MD, USA.

出版信息

J Pediatr Orthop. 2012 Oct-Nov;32(7):647-57. doi: 10.1097/BPO.0b013e3182694f18.

Abstract

BACKGROUND

Early onset scoliosis (EOS) is a potentially fatal, challenging group of diseases the management of which has markedly changed in the last decade. The purpose of this review is to provide the reader with a brief description of each of these new therapeutic modalities, their indications for use, and early clinical results.

METHODS

A systematic review of peer-reviewed publications and abstracts related to the treatment of EOS in the last decade was carried out and synthesized into a review of modern treatment methods.

RESULTS

Recent advances in techniques and understanding of preserving the thoracic space have improved the morbidity and mortality of children with progressive EOS. Derotational casting may be used in younger patients with curves between 25 and 60 degrees. The vertical expandable prosthetic titanium rib is best suited for patients with thoracic insufficiency syndrome. Single or dual growing rods may be used alone or in combination with vertical expandable prosthetic titanium rib to treat patients with progressive EOS who are not candidates for casting. Shilla technique is an alternative to growing rods that avoids the morbidity of repeated lengthenings but is not as well proven as the techniques described above. Other methods such as automatic growing rods and growth modulation techniques are still investigational, and their role needs to be defined after further study.

CONCLUSIONS

Recent advances have improved the treatment of children with EOS. Treatment continues to be challenging with complication rates higher than treatment of idiopathic scoliosis.

LEVEL OF EVIDENCE

Level V.

摘要

背景

早发性脊柱侧凸(EOS)是一组具有潜在致命性且极具挑战性的疾病,在过去十年中其治疗方法发生了显著变化。本综述的目的是向读者简要介绍这些新的治疗方式、它们的使用指征以及早期临床结果。

方法

对过去十年中与EOS治疗相关的同行评审出版物和摘要进行系统综述,并综合成一篇现代治疗方法的综述。

结果

在保留胸廓空间的技术和认识方面的最新进展改善了进行性EOS患儿的发病率和死亡率。去旋转支具可用于年龄较小、侧弯角度在25至60度之间的患者。垂直可扩展人工钛肋骨最适合胸廓发育不全综合征患者。单根或双根生长棒可单独使用,或与垂直可扩展人工钛肋骨联合使用,以治疗不适合使用支具的进行性EOS患者。席拉技术是生长棒的一种替代方法,可避免反复延长带来的并发症,但不如上述技术成熟。其他方法,如自动生长棒和生长调节技术仍在研究中,其作用需要进一步研究后确定。

结论

最近的进展改善了EOS患儿的治疗。治疗仍然具有挑战性,并发症发生率高于特发性脊柱侧凸的治疗。

证据级别

V级。

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