[Bone and calcium metabolism in adult hypothyroidism (author's transl)].

A study of blood and urinary calcium and phosphorus, 25 hydroxyvitamin D plasma level (25 OH D3), bone radiology and hystology is performed in 12 hypothyroïd adult patients. This study confirms the notion of myxoedematous ostéopetrosis. Radiologic and histologic findings shows an osteocondensation, more important on the skull, and augmentation of cortical thickness of the bones is noted. Quantitative histologic findings, shows some signs of diminution of bone cellular activity. Low plasma level of 25 OH D3 in these patients is discussed in the view of an event of a disturb in the metabolism of D-vitamin in hypothyroïdism.