Arlet P, Latorzeff S, Bayard F, Le Tallec Y
Sem Hop. 1979;55(33-34):1488-92.
A study of blood and urinary calcium and phosphorus, 25 hydroxyvitamin D plasma level (25 OH D3), bone radiology and hystology is performed in 12 hypothyroïd adult patients. This study confirms the notion of myxoedematous ostéopetrosis. Radiologic and histologic findings shows an osteocondensation, more important on the skull, and augmentation of cortical thickness of the bones is noted. Quantitative histologic findings, shows some signs of diminution of bone cellular activity. Low plasma level of 25 OH D3 in these patients is discussed in the view of an event of a disturb in the metabolism of D-vitamin in hypothyroïdism.
对12名成年甲状腺功能减退患者进行了血液和尿液中的钙、磷、25羟维生素D血浆水平（25-OH D3）、骨骼放射学和组织学研究。这项研究证实了黏液性水肿性骨硬化症的概念。放射学和组织学结果显示骨密度增加，在颅骨上更为明显，且注意到骨骼皮质厚度增加。定量组织学结果显示骨细胞活性有一些降低的迹象。从甲状腺功能减退症中维生素D代谢紊乱这一事件的角度讨论了这些患者25-OH D3血浆水平较低的情况。
