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非综合征型单一颅缝早闭患者 Chiari Ⅰ型畸形的不对称性。

Asymmetric laterality of Chiari type I malformation in patients with non-syndromic single-suture craniosynostosis.

机构信息

Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland.

出版信息

Acta Neurochir (Wien). 2012 Nov;154(11):2103-7. doi: 10.1007/s00701-012-1470-6. Epub 2012 Sep 7.

DOI:10.1007/s00701-012-1470-6
PMID:22955872
Abstract

BACKGROUND

Chiari type I malformation is a frequent incidental finding commonly associated with craniosynostosis. However, there seems to be a paucity of literature concerning the asymmetry of tonsillar herniation in patients with non-syndromic single-suture craniosynostosis.

METHODS

To study the asymmetry in this cohort, measurements of the right and left tonsils were made from sagittal images from both pre-operative and post-operative images from 11 patients with non-syndromic single-suture craniosynostosis.

RESULTS

Pre-operatively, the mean difference between the caudal descent of all tonsils ranged from 0 to 7 mm, with a mean difference between sides of 2.45 mm. In three cases, cerebellar tonsils were symmetrically herniated. Post-operatively, the mean difference between caudal descent of all tonsils ranged from 0 to 4 mm, with a mean difference between sides of 1.45 mm. Four were symmetrically herniated. In patients with non-syndromic single-suture craniosynostosis, the tonsillar herniation is asymmetric in the majority of cases.

CONCLUSIONS

Asymmetry of cerebellar tonsil herniation is a frequent finding in this cohort. The right tonsil is more inferiorly located in majority of cases, with predominance to the synostotic suture side in asymmetric craniosynostosis cases.

摘要

背景

Chiari Ⅰ 型畸形是一种常见的偶发发现,通常与颅缝早闭有关。然而,关于非综合征性单缝颅缝早闭患者的扁桃体疝不对称性似乎文献很少。

方法

为了研究该队列的不对称性,对 11 例非综合征性单缝颅缝早闭患者的术前和术后矢状图像进行了右、左扁桃体的测量。

结果

术前,所有扁桃体下降的平均差异在 0 到 7mm 之间,侧间差异平均为 2.45mm。在 3 例中,小脑扁桃体对称疝出。术后,所有扁桃体下降的平均差异在 0 到 4mm 之间,侧间差异平均为 1.45mm。4 例为对称疝出。在非综合征性单缝颅缝早闭患者中,扁桃体疝多数情况下不对称。

结论

小脑扁桃体疝的不对称性是本队列中的一个常见发现。在大多数情况下,右侧扁桃体位置较低,在不对称性颅缝早闭病例中,偏向于早闭缝的一侧。

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