Ocul Immunol Inflamm. 2012 Oct;20(5):384-6. doi: 10.3109/09273948.2012.710705. Epub 2012 Sep 7.
To report a case of progressive outer retinal necrosis (PORN) presenting as a cherry red spot.
Case report.
A 53-year-old woman with recently diagnosed HIV and varicella-zoster virus (VZV) aseptic meningitis developed rapid sequential vision loss in both eyes over 2 months. Her exam showed a "cherry red spot" in both maculae with peripheral atrophy and pigmentary changes, consistent with PORN. Due to her late presentation and the rapid progression of her condition, she quickly developed end-stage vision loss in both eyes.
PORN should be considered within the differential diagnosis of a "cherry red spot." Immune-deficient patients with a history of herpetic infection who present with visual loss warrant prompt ophthalmological evaluation.
报告一例表现为樱桃红斑的进行性外层视网膜坏死(PORN)。
病例报告。
一名 53 岁女性,患有新近诊断的 HIV 和水痘带状疱疹病毒(VZV)无菌性脑膜炎,在 2 个月内双眼视力迅速连续下降。她的检查显示双眼黄斑均有“樱桃红斑”,伴有周边萎缩和色素变化,符合 PORN 的表现。由于她就诊较晚,病情迅速进展,她的双眼很快发展为终末期视力丧失。
在“樱桃红斑”的鉴别诊断中应考虑 PORN。有疱疹感染史的免疫功能低下患者出现视力丧失时应及时进行眼科评估。