离子液体支撑的磺酰叠氮的合成及其在重氮转移反应中的应用。

Synthesis of ionic liquid-supported sulfonyl azide and its application in diazotransfer reaction.

机构信息

Department of Chemistry, Birla Institute of Technology and Science, Pilani 333031, Rajasthan, India.

出版信息

J Org Chem. 2012 Oct 5;77(19):8787-91. doi: 10.1021/jo301529b. Epub 2012 Sep 19.

Abstract

The paper describes synthesis of a novel ionic liquid-supported sulfonyl azide and its applications as diazotransfer reagent of active methylene compounds as well as deformylative diazo transfer reagent. The diazo compounds were isolated in excellent yields (82-94%) and high purity. The method offers better separation of product and reagent. This method is experimentally simple and mild, and requires very short reaction time.

摘要

本文描述了一种新型离子液体支撑的磺酰叠氮的合成及其作为活泼亚甲基化合物的重氮转移试剂以及去甲酰基重氮转移试剂的应用。重氮化合物以优异的收率（82-94%）和高纯度分离得到。该方法提供了更好的产物和试剂分离。该方法实验操作简单温和，反应时间极短。