Kelley Scott D
Crit Care. 2012 Sep 4;16(5):446. doi: 10.1186/cc11464.
The number needed to treat can be calculated for ventilator-associated pneumonia reduction strategies such as subglottic secretion drainage technology based on previous work establishing its relative risk reduction. Assuming an incidence of 4%, employing subglottic secretion drainage in 33 patients will prevent one case of ventilator-associated pneumonia, and thus potentially 4 cases annually in an average hospital in the United States. With a previously described limit of £300 ($470 USD) additional cost per 10 days of ventilation as a threshold of investment for technologies to reduce ventilator-associated pneumonia, subglottic secretion drainage technology is both clinically and cost effective.
基于先前确定其相对风险降低率的研究工作，可以针对诸如声门下分泌物引流技术等呼吸机相关性肺炎减少策略计算需治疗人数。假设发病率为4%，对33例患者采用声门下分泌物引流可预防1例呼吸机相关性肺炎，因此在美国一家普通医院每年可能预防4例。以先前描述的每10天通气额外成本300英镑（470美元）作为减少呼吸机相关性肺炎技术的投资阈值，声门下分泌物引流技术在临床和成本效益方面均具有优势。
