Rukholm Gavin, Farrokhyar Forough, Reid Diane
McMaster University Medical Centre, Department of Otolaryngology, Head and Neck Surgery, 1200 Main St. West, Hamilton, ON, L8N 3Z5, Canada.
Int J Pediatr Otorhinolaryngol. 2012 Nov;76(11):1637-41. doi: 10.1016/j.ijporl.2012.07.036. Epub 2012 Sep 5.
Retrospective chart review of all infants who underwent PDA ligation surgery at a tertiary care academic hospital between July 2003 and July 2010. Data on patient age, gender, weight, method of PDA ligation, and results of NPL scoping were collected, as well as patient co-morbidities post PDA ligation.
One hundred and fifteen patients underwent PDA ligation surgery. Four patients were excluded due to bilateral vocal cord paralysis. Of the remaining 111 patients, nineteen patients (17.1%) were found to have LVCP. Low birth weight was identified as a significant risk factor for LVCP (p=0.002). Gastroesophageal reflux was identified as a significant co-morbidity associated with LVCP post PDA ligation (p=0.002). Only 0.9% of patients were scoped pre-operatively, and 27.9% were scoped postoperatively.
LVCP is associated with multiple morbidities. The authors strongly recommend routine post-operative scoping of all patients post PDA ligation surgery, and preoperative scoping when possible. A prospective study is warranted, in order to confirm the prevalence of LVCP as well as risk factors and associated co-morbidities.
对2003年7月至2010年7月期间在一家三级医疗学术医院接受PDA结扎手术的所有婴儿进行回顾性病历审查。收集患者年龄、性别、体重、PDA结扎方法、NPL检查结果以及PDA结扎术后患者的合并症数据。
115例患者接受了PDA结扎手术。4例因双侧声带麻痹被排除。在其余111例患者中,19例(17.1%)被发现患有LVCP。低出生体重被确定为LVCP的一个重要风险因素(p = 0.002)。胃食管反流被确定为与PDA结扎术后LVCP相关的一个重要合并症(p = 0.002)。术前仅0.9%的患者进行了检查,术后27.9%的患者进行了检查。
LVCP与多种合并症相关。作者强烈建议对所有PDA结扎手术后的患者进行常规术后检查,如有可能进行术前检查。有必要进行一项前瞻性研究,以确认LVCP的患病率以及风险因素和相关合并症。