• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

感音神经性听力损失在背景噪声中表现出时间编码能力下降。

Diminished temporal coding with sensorineural hearing loss emerges in background noise.

机构信息

Department of Speech, Language and Hearing Sciences, Purdue University, West Lafayette, Indiana, USA.

出版信息

Nat Neurosci. 2012 Oct;15(10):1362-4. doi: 10.1038/nn.3216. Epub 2012 Sep 9.

DOI:10.1038/nn.3216
PMID:22960931
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3458164/
Abstract

Behavioral studies in humans suggest that sensorineural hearing loss (SNHL) decreases sensitivity to the temporal structure of sound, but neurophysiological studies in mammals provide little evidence for diminished temporal coding. We found that SNHL in chinchillas degraded peripheral temporal coding in background noise substantially more than in quiet. These results resolve discrepancies between previous studies and help to explain why perceptual difficulties in hearing-impaired listeners often emerge in noisy situations.

摘要

行为学研究表明，感音神经性听力损失（SNHL）会降低人对声音时间结构的敏感性，但哺乳动物的神经生理学研究几乎没有提供证据表明时间编码能力下降。我们发现，在背景噪声中，SNHL 会大大降低南美栗鼠的外周时间编码，比在安静环境中更为严重。这些结果解决了先前研究之间的差异，并有助于解释为什么听力受损者在嘈杂环境中经常出现感知困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a272/3458164/ef11925cc2fc/nihms-401421-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a272/3458164/52397fb10ecb/nihms-401421-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a272/3458164/a31ed73aca6a/nihms-401421-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a272/3458164/ef11925cc2fc/nihms-401421-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a272/3458164/52397fb10ecb/nihms-401421-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a272/3458164/a31ed73aca6a/nihms-401421-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a272/3458164/ef11925cc2fc/nihms-401421-f0003.jpg

相似文献

1
Diminished temporal coding with sensorineural hearing loss emerges in background noise.感音神经性听力损失在背景噪声中表现出时间编码能力下降。
Nat Neurosci. 2012 Oct;15(10):1362-4. doi: 10.1038/nn.3216. Epub 2012 Sep 9.
2
Effects of sensorineural hearing loss on temporal coding of harmonic and inharmonic tone complexes in the auditory nerve.感音神经性听力损失对听神经中谐波和非谐波复合音的时间编码的影响。
Adv Exp Med Biol. 2013;787:109-18. doi: 10.1007/978-1-4614-1590-9_13.
3
Magnified Neural Envelope Coding Predicts Deficits in Speech Perception in Noise.放大的神经包络编码可预测噪声环境下言语感知的缺陷。
J Neurosci. 2017 Aug 9;37(32):7727-7736. doi: 10.1523/JNEUROSCI.2722-16.2017. Epub 2017 Jul 10.
4
Temporal modulation transfer functions measured from auditory-nerve responses following sensorineural hearing loss.测量感音神经性听力损失后听神经反应的时变调制传递函数。
Hear Res. 2012 Apr;286(1-2):64-75. doi: 10.1016/j.heares.2012.02.004. Epub 2012 Feb 16.
5
Sensorineural hearing loss amplifies neural coding of envelope information in the central auditory system of chinchillas.感音神经性听力损失增强了毛丝鼠中枢听觉系统中包络信息的神经编码。
Hear Res. 2014 Mar;309:55-62. doi: 10.1016/j.heares.2013.11.006. Epub 2013 Dec 4.
6
Divergent Auditory Nerve Encoding Deficits Between Two Common Etiologies of Sensorineural Hearing Loss.两种常见感音神经性听力损失病因的听觉神经编码差异。
J Neurosci. 2019 Aug 28;39(35):6879-6887. doi: 10.1523/JNEUROSCI.0038-19.2019. Epub 2019 Jul 8.
7
Distorted Tonotopy Severely Degrades Neural Representations of Connected Speech in Noise following Acoustic Trauma.声创伤后，扭曲的音调拓扑严重降低了语音连接在噪声中的神经表示。
J Neurosci. 2022 Feb 23;42(8):1477-1490. doi: 10.1523/JNEUROSCI.1268-21.2021. Epub 2022 Jan 4.
8
Envelope coding in auditory nerve fibers following noise-induced hearing loss.噪声性听力损失后听神经纤维的包络编码。
J Assoc Res Otolaryngol. 2010 Dec;11(4):657-73. doi: 10.1007/s10162-010-0223-6. Epub 2010 Jun 16.
9
Frequency difference limens in normal and sensorineural hearing impaired chinchillas.正常及感音神经性听力受损的栗鼠的频率差异阈限
J Acoust Soc Am. 1989 Mar;85(3):1302-13. doi: 10.1121/1.397461.
10
Spectro-temporal analysis in normal-hearing and cochlear-impaired listeners.正常听力和人工耳蜗植入听众的频谱-时间分析
J Acoust Soc Am. 1988 Oct;84(4):1325-31. doi: 10.1121/1.396631.

引用本文的文献

1
Cochlear Tuning in Early Aging Estimated with Three Methods.用三种方法估计早期衰老中的耳蜗调谐。
Trends Hear. 2025 Jan-Dec;29:23312165251364675. doi: 10.1177/23312165251364675. Epub 2025 Jul 29.
2
Effect of digital noise reduction processing on subcortical speech encoding and relationship to behavioral outcomes.数字降噪处理对皮质下语音编码的影响及其与行为结果的关系。
Sci Rep. 2025 Jul 1;15(1):22198. doi: 10.1038/s41598-025-07652-9.
3
Evidence for the Auditory Nerve Generating Envelope Following Responses When Measured from Eardrum Electrodes.

本文引用的文献

1
Auditory brainstem responses predict auditory nerve fiber thresholds and frequency selectivity in hearing impaired chinchillas.听性脑干反应可预测听力受损南美栗鼠的听神经纤维阈值和频率选择性。
Hear Res. 2011 Oct;280(1-2):236-44. doi: 10.1016/j.heares.2011.06.002. Epub 2011 Jun 15.
2
Envelope coding in auditory nerve fibers following noise-induced hearing loss.噪声性听力损失后听神经纤维的包络编码。
J Assoc Res Otolaryngol. 2010 Dec;11(4):657-73. doi: 10.1007/s10162-010-0223-6. Epub 2010 Jun 16.
3
Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced hearing loss.
从鼓膜电极测量时听觉神经产生包络跟随反应的证据。
J Assoc Res Otolaryngol. 2025 Apr;26(2):147-162. doi: 10.1007/s10162-025-00979-0. Epub 2025 Mar 6.
4
Auditory decision-making deficits after permanent noise-induced hearing loss.永久性噪声性听力损失后的听觉决策缺陷。
Sci Rep. 2025 Jan 15;15(1):2104. doi: 10.1038/s41598-024-83374-8.
5
Effect of digital noise-reduction processing on subcortical speech encoding and relationship to behavioral outcomes.数字降噪处理对皮质下语音编码的影响及其与行为结果的关系。
bioRxiv. 2024 Oct 28:2024.10.28.620630. doi: 10.1101/2024.10.28.620630.
6
The impact of amplification on quality of life in women with Turner syndrome.特纳综合征女性中扩增对生活质量的影响。
Orphanet J Rare Dis. 2024 Mar 13;19(1):119. doi: 10.1186/s13023-024-03122-z.
7
Neural hyperactivity and altered envelope encoding in the central auditory system: Changes with advanced age and hearing loss.中枢听觉系统的神经活动亢进和包络编码改变：与年龄增长和听力损失相关的变化。
Hear Res. 2024 Feb;442:108945. doi: 10.1016/j.heares.2023.108945. Epub 2023 Dec 23.
8
Domain-specific hearing-in-noise performance is associated with absolute pitch proficiency.特定领域的噪声下听觉能力与绝对音高能力有关。
Sci Rep. 2022 Sep 29;12(1):16344. doi: 10.1038/s41598-022-20869-2.
9
Underlying neural mechanisms of degraded speech intelligibility following noise-induced hearing loss: The importance of distorted tonotopy.噪声性听力损失后语音可懂度下降的潜在神经机制：扭曲的音调拓扑结构的重要性。
Hear Res. 2022 Dec;426:108586. doi: 10.1016/j.heares.2022.108586. Epub 2022 Jul 22.
10
Distorted Tonotopy Severely Degrades Neural Representations of Connected Speech in Noise following Acoustic Trauma.声创伤后，扭曲的音调拓扑严重降低了语音连接在噪声中的神经表示。
J Neurosci. 2022 Feb 23;42(8):1477-1490. doi: 10.1523/JNEUROSCI.1268-21.2021. Epub 2022 Jan 4.
雪上加霜：“暂时性”噪声性听力损失后蜗神经变性
J Neurosci. 2009 Nov 11;29(45):14077-85. doi: 10.1523/JNEUROSCI.2845-09.2009.
4
Abnormal processing of temporal fine structure in speech for frequencies where absolute thresholds are normal.对于绝对阈值正常的频率，语音中时间精细结构的异常处理。
J Acoust Soc Am. 2009 Jan;125(1):27-30. doi: 10.1121/1.2939125.
5
The role of temporal fine structure processing in pitch perception, masking, and speech perception for normal-hearing and hearing-impaired people.时间精细结构处理在正常听力和听力受损人群的音高感知、掩蔽及言语感知中的作用。
J Assoc Res Otolaryngol. 2008 Dec;9(4):399-406. doi: 10.1007/s10162-008-0143-x. Epub 2008 Oct 15.
6
Effect of auditory-nerve response variability on estimates of tuning curves.听神经反应变异性对调谐曲线估计的影响。
J Acoust Soc Am. 2007 Dec;122(6):EL203-9. doi: 10.1121/1.2794880.
7
An Evaluation of the BKB-SIN, HINT, QuickSIN, and WIN Materials on Listeners With Normal Hearing and Listeners With Hearing Loss.对正常听力听众和听力损失听众使用BKB-SIN、HINT、QuickSIN和WIN材料的评估。
J Speech Lang Hear Res. 2007 Aug;50(4):844-56. doi: 10.1044/1092-4388(2007/059).
8
Speech perception problems of the hearing impaired reflect inability to use temporal fine structure.听力受损者的言语感知问题反映出其无法利用时间精细结构。
Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18866-9. doi: 10.1073/pnas.0607364103. Epub 2006 Nov 20.
9
Frequency discrimination of complex tones by hearing-impaired subjects: Evidence for loss of ability to use temporal fine structure.听力受损受试者对复合音的频率辨别：丧失利用时间精细结构能力的证据。
Hear Res. 2006 Dec;222(1-2):16-27. doi: 10.1016/j.heares.2006.08.007. Epub 2006 Oct 6.
10
Relationship between the auditory brainstem response and auditory nerve thresholds in cats with hearing loss.听力损失猫的听觉脑干反应与听神经阈值之间的关系。
Hear Res. 2001 Jun;156(1-2):44-52. doi: 10.1016/s0378-5955(01)00264-7.