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伊巴丹大学学院医院坏死性筋膜炎的回顾性评估。

Retrospective evaluation of necrotizing fasciitis in University College Hospital, Ibadan.

作者信息

Obimakinde O S, Okoje V N, Akinmoladun V I, Fasola A O, Arotiba J T

机构信息

Department of Dental and Maxillofacial Surgery, University Teaching Hospital, Ado Ekiti, Nigeria.

出版信息

Niger J Clin Pract. 2012 Jul-Sep;15(3):344-8. doi: 10.4103/1119-3077.100644.

Abstract

CONTEXT

Cervicofacial necrotizing fasciitis (CNF), although a potentially fatal fulminant infection has been largely under-reported in the dental literature.

AIMS

To report our experience with cases seen and treated at the University College Hospital, Ibadan, Nigeria.

SETTINGS AND DESIGN

A descriptive retrospective clinical study.

MATERIALS AND METHODS

A retrospective survey of cases treated between January 2002 and January 2007 was done. Diagnosis of CNF was established by fascia necrosis found on surgical exploration. Patients' age, sex, medical status, etiology of infection, bacteriology, and treatment received and complications were reviewed.

STATISTICAL ANALYSIS USED

SPSS version 15.

RESULTS

Of the 48 cases of cervicofacial infection admitted during the study period, only 12 cases of CNF were found. Male:Female ratio was 4:8. The mean age of patients was 58.83 ± 11.91 years while the age range was 42-83 years. Those that had immunocompromised medical conditions included three cases each of diabetes mellitus and chronic nutritional anaemia and one case of retroviral infection. Mixed bacterial isolates of anaerobes and enterobacteriaceae were found in 10 cases while beta hemolytic streptococci were the sole isolate in two cases. All patients had serial debridement combined with intravenous antibiotic medications. Complications included anterior chest wall infection in three patients and one case of pleural effusion. The only mortality occurred in the patient with retroviral infection.

CONCLUSIONS

We advocate early recognition, surgical debridement and intensive medical care for treatment of CNF in order to reduce morbidity and mortality from this condition.

摘要

背景

尽管颈面部坏死性筋膜炎(CNF)是一种潜在致命的暴发性感染,但在牙科文献中大多未得到充分报道。

目的

报告我们在尼日利亚伊巴丹大学学院医院诊治病例的经验。

设置与设计

一项描述性回顾性临床研究。

材料与方法

对2002年1月至2007年1月期间治疗的病例进行回顾性调查。通过手术探查发现筋膜坏死来确诊CNF。回顾患者的年龄、性别、健康状况、感染病因、细菌学、接受的治疗及并发症。

所用统计分析方法

SPSS 15版。

结果

在研究期间收治的48例颈面部感染病例中,仅发现12例CNF。男女比例为4:8。患者平均年龄为58.83±11.91岁,年龄范围为42 - 83岁。有免疫功能低下健康状况的患者包括3例糖尿病患者、3例慢性营养性贫血患者和1例逆转录病毒感染患者。10例患者分离出厌氧菌和肠杆菌科的混合细菌,2例患者仅分离出β溶血性链球菌。所有患者均接受了系列清创术并联合静脉使用抗生素药物。并发症包括3例患者出现前胸壁感染和1例胸腔积液。唯一的死亡病例是逆转录病毒感染患者。

结论

我们主张早期识别、手术清创和强化医疗护理来治疗CNF,以降低该病的发病率和死亡率。

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