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空肠回肠闭锁:关于临床表现及预后的两年初步研究

Jejuno-ileal atresia: a 2-year preliminary study on presentation and outcome.

作者信息

Ekwunife O H, Oguejiofor I C, Modekwe V I, Osuigwe A N

机构信息

Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.

出版信息

Niger J Clin Pract. 2012 Jul-Sep;15(3):354-7. doi: 10.4103/1119-3077.100647.

Abstract

BACKGROUND/AIM: Intestinal atresia is a common cause of neonatal intestinal obstruction. Jejuno-ileum is the commonest site of intestinal atresia. Reports on Jejunoileal atresia in developing countries are still few. The purpose of this study is to determine the presentation and management outcomes of neonates with Jejunoileal atresia treated in our hospital.

MATERIALS AND METHODS

Detailed data on all babies that presented and were treated within the study period (November2008-November, 2010) were kept and analyzed. A management protocol was put up and maintained.

RESULT

A total of 9 babies (7males and 2 females) were treated. They were aged 2 hours to 13 days. Their weight ranged from 1.7kg to 3.3kg. Apart from one baby which presented within 2hrs with prenatal ultrasound diagnosis, others had bilious vomiting from the first day of birth, abdominal distension and delayed or absent passage of meconium. Even though symptoms developed on the first day of birth, presentation to the surgical unit was delayed 72hours and beyond in most patients.Type I atresia is commonest (no=4).There is associated gut malrotation in 2 babies. Five babies had complications which included surgical site infection, sepsis, prolonged vomiting post operatively, aspiration, rupture of dilated proximal segment after membrane excision, entero-cutaneous fistula and malnutrition. Three babies died giving a mortality of 33.3%. Mortality is commoner in types IIIb and IV.

CONCLUSION

Mortality is higher in complex atresia which most times will require neonatal intensive care and parenteral nutrition facilities. These are still lacking in our institution. Providing these facilities will further improve outcome.

摘要

背景/目的:肠道闭锁是新生儿肠梗阻的常见原因。空肠-回肠是肠道闭锁最常见的部位。发展中国家关于空肠回肠闭锁的报道仍然很少。本研究的目的是确定在我院接受治疗的空肠回肠闭锁新生儿的临床表现及治疗结果。

材料与方法

记录并分析了在研究期间(2008年11月至2010年11月)就诊并接受治疗的所有婴儿的详细数据。制定并维持了一套治疗方案。

结果

共治疗9例婴儿(7例男性,2例女性)。年龄从2小时至13天不等。体重在1.7千克至3.3千克之间。除1例在出生2小时内通过产前超声诊断就诊外,其他婴儿自出生第一天起就出现胆汁性呕吐、腹胀以及胎粪排出延迟或未排出。尽管症状在出生第一天就已出现,但大多数患者直到72小时及以后才到外科就诊。I型闭锁最常见(4例)。2例婴儿伴有肠旋转不良。5例婴儿出现了并发症,包括手术部位感染、败血症、术后长期呕吐、误吸、膜切除后扩张近端肠段破裂、肠皮肤瘘和营养不良。3例婴儿死亡,死亡率为33.3%。IIIb型和IV型闭锁的死亡率更高。

结论

复杂闭锁的死亡率更高,大多数情况下需要新生儿重症监护和肠外营养设施。而我院仍然缺乏这些设施。提供这些设施将进一步改善治疗结果。

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