儿童和青少年口腔牙槽软组织肉瘤：两例报告并文献复习
Oral alveolar soft part sarcoma in childhood and adolescence: report of two cases and review of literature.
作者信息
Argyris Prokopios P, Reed Robyn C, Manivel J Carlos, Lopez-Terrada Dolores, Jakacky Jared, Cayci Zuzan, Tosios Konstantinos I, Pambuccian Stefan E, Thompson Lester D R, Koutlas Ioannis G
机构信息
Department of Oral Pathology and Medicine, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
出版信息
Head Neck Pathol. 2013 Mar;7(1):40-9. doi: 10.1007/s12105-012-0395-y. Epub 2012 Sep 8.
Abstract
Alveolar soft part sarcoma (ASPS) constitutes a rare soft tissue malignant neoplasm comprising less than 1 % of all soft tissue sarcomas. ASPS demonstrates a strong predilection for adolescents and young adults, with a female predominance reported. The head and neck region is the most commonly affected region in pediatric patients with the tongue and orbit affected most commonly. Herein we present the clinical, radiographic, histopathologic, immunohistochemical and molecular features of two examples of ASPS affecting the oral cavity of 4 and 13 year-old boys, along with a focused review of the literature on intraoral ASPS in pediatric patients.
摘要
肺泡软组织肉瘤（ASPS）是一种罕见的软组织恶性肿瘤，占所有软组织肉瘤的比例不到1%。ASPS在青少年和年轻成年人中具有明显的偏好，据报道女性居多。头颈部是小儿患者中最常受累的区域，其中舌头和眼眶最常受到影响。在此，我们展示了两例分别影响4岁和13岁男孩口腔的ASPS的临床、影像学、组织病理学、免疫组织化学和分子特征，并对小儿患者口腔内ASPS的文献进行了重点综述。
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